BNIP3 Antibody (EPR4034) (NBP1-95586)

BNIP3 Antibody (EPR4034) (NBP1-95586) (0.1 mL)

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	Catalog Number	NBP1-95586
	Size(s)	0.1 mL	Price:
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anti-BCL2/adenovirus E1B 19 kDa protein-interacting protein 3 antibody, anti-BCL2/adenovirus E1B 19kD-interacting protein 3 antibody, anti-Nip3 antibody, anti-NIP3 antibody, anti-BCL2/adenovirus E1B 19kDa interacting protein 3 antibody

BNIP3 Antibody (EPR4034) Summary:

Species:	Hu, Mu, Rt	Gene:	BNIP3
Applications:	WB, ICC, IF, IHC-P	Purity:	Tissue culture supernatant
Clonality:	Monoclonal	Host:	Rabbit
Publications:

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Lysates	Primary Antibodies
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BNIP3 Antibody (EPR4034) Details:

Clone:	EPR4034
Immunogen:	A synthetic peptide corresponding to residues in human NIP3 / BNIP3 was used as an immunogen.

Species Reactivity:

Human, Mouse, Rat. For Mouse and Rat this antibody is recommended for Western Blot only.

Applications:

Uses:	This product is useful in Western Blot,Immunohistochemistry,Immunocytochemistry,
Dilutions:	Immunocytochemistry 1:100 - 250, Immunohistochemistry-Paraffin 1:50 - 100, Western Blot 1:1000-10000, Immunofluorescence
Unit Size:	0.1 mL
Concentration:	This product is unpurified. Concentration is not relevant.

Packaging:

Storage:	Store at -20°C. Avoid freeze-thaw cycles.
Buffer:	Antibody buffer, sodium azide, glycerol, and BSA.
Preservative:	0.01% Sodium Azide
Limitations:	This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months.

Gene Symbol: BNIP3

Entrez:	664 (Human)
Uniprot:	Q12983 (Human)

Related Genes:

Background:

NIP3 / BNIP3 is a member of the BCL2/adenovirus E1B 19 kDa-interacting protein (BNIP) family. It interacts with the E1B 19 kDa protein which is responsible for the protection of virally-induced cell death, as well as E1B 19 kDa-like sequences of BCL2, also an apoptotic protector. NIP3 / BNIP3 contains a BH3 domain and a transmembrane domain, which have been associated with pro-apoptotic function. The dimeric mitochondrial protein is known to induce apoptosis, even in the presence of BCL2.

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BNIP3 Antibody (EPR4034) Images (3)

	Western Blot: BNIP3 Antibody (EPR4034) [NBP1-95586] - SY5Y treated with camptothecin, (D) SH-SY5Y, and (E) MCF-7 treated with Cocl2 cell lysates using anti-NIP3 / BNIP3.

	Immunohistochemistry-Paraffin: BNIP3 Antibody (EPR4034) [NBP1-95586] - NIP3 / BNIP3.

	Immunofluorescence: BNIP3 Antibody (EPR4034) [NBP1-95586] SH-SY5Y cells using anti-NIP3 / BNIP3.