Apolipoprotein A-I/ApoA1 Antibody (EP1368Y)

Produced using Abcam's RabMab® technology. RabMab® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

Apolipoprotein A1 (apo A1) is the major polypeptide of the human plasma high density lipoprotein (HDL). The structure and function of the apo A1 gene are of interest because of the inverse correlation shown between HDL levels and coronary heart disease (1). The 267 amino acid precursor initially undergoes intracellular co-translational proteolytic cleavage into proapoA-I. ProapoA-I is secreted from the cell and was isolated from thoracic duct lymph in the apoA-I1 isoform position. Results indicate that apo A1 is present in human plasma, and undergoes post-translational proteolytic cleavage to mature plasma apoA-I (2). Cleavage of this protein with cyanogen bromide yields four fragments designated in the order of elution from Bio-Gel P-30 as CNBr I, II, III, and IV (3).

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 2 applications: ELISA, ICC/IF.

Showing Publications 1 - 2 of 2.

Publications using NB110-55465	Applications	Species
Aseem O, Smith BT, Cooley MA et al. Cubilin Maintains Blood Levels of HDL and Albumin. J Am Soc Nephrol 2013-12-19 [PMID: 24357674] (ELISA)	ELISA
Krueger WH, Tanasijevic B, Barber V et al. Cholesterol-Secreting and Statin-Responsive Hepatocytes from Human ES and iPS Cells to Model Hepatic Involvement in Cardiovascular Health. PLoS One 2013-07-11 [PMID: 23874411] (ICC/IF, Human)	ICC/IF	Human

Array NB110-55465

• Apolipoprotein A-I/ApoA1 Antibodies
• Apolipoprotein A-I/ApoA1 Antibody Pair
• Apolipoprotein A-I/ApoA1 ELISA Kits
• Apolipoprotein A-I/ApoA1 Lysate
• Apolipoprotein A-I/ApoA1 Proteins
• Apolipoprotein A-I/ApoA1 Proteins and Enzyme
• Apolipoprotein A-I/ApoA1 ELISAs