ApoE Lysate (NBL1-07621)

ApoE Lysate

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ApoE Lysate Summary:
Applications:WB
Gene:APOE
Purity:Protein
Specificity:Homo sapiens apolipoprotein E (APOE), mRNA.
 
Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur.
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ApoE Lysate Details:
Immunogen:The lysate was created in HEK293T cells, using plasmid ID RC200395 and based on accession number NM_000041. The protein contains a C-terminal DDK tag.
Epitope:C-terminal Myc/DDK
Lysate Details:
Type: OverexpressionLife Stage: Adult
Protein State: Native Tissue Condition: Normal
Sub-cellular Fraction: Whole
Applications:
Uses:This product is intended for use as a positive control in Western Blot. You will receive the lysate (100ug), and an empty vector negative control (100 ug).
Dilutions:Western Blot
TMW:34.2 kDa
Unit Size:0.1 mg
Concentration:1.0 mg/ml
Notes:
This product is manufactured by and sold under license from OriGene Technologies and its use is limited solely for research purposes. Please note that “1 mg/ml” refers to the total protein concentration and that the specific protein concentration is not determined at this time.
Packaging:
Storage:Store at -80 °C. Avoid freeze-thaw cycles.
Buffer:RIPA buffer
Limitations:This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months.
Gene Symbol: APOE
Entrez348 (Human)
Swiss ProtNM_000041 (Human)
 
Background:

Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells. ApoE is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. The APOE gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. [provided by RefSeq]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

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ApoE Lysate Images (1)
Western Blot: ApoE Lysate [NBL1-07621] - Western Blot experiments. Left-Control; Right -Over-expression Lysate for APOE
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