ApoE Antibody (NB100-1530)
ApoE Antibody
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Distributor Data...
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anti-APOE antibody, Anti-MGC1571 antibody, anti-late onset antibody, Anti-Apoprotein antibody, anti-apolipoprotein E3 antibody, anti-apolipoprotein E antibody, anti-Alzheimer disease 2 (APOE*E4-associated antibody, anti-AD2 antibody, |
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ApoE Antibody Summary: | | Gene: | APOE |
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| Purity: | Immunogen affinity purified |
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| Host: | Goat |
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| | | | Publications: | Antibody has been mentioned in at least 1 Publication. |
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| | Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur. |
View Additional ApoE Products ApoE Antibody Details: | Isotype: | IgG |
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| Immunogen: | Synthetic peptide with sequence C-VGTSAAPVPSDNH, representing the C Terminus of the human protein according to NP_000032.1 |
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| Epitope: | C Terminus |
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| Uses: | This antibody is useful for Peptide ELISA, Western Blot and Immunohisochemisrty. Approx. 36kDa band observed in Human Brain lysates (calculated MW of 36.2kDa according to NP_000032.1). In paraffin embedded Human Liver shows extra-cellular staining between hepatocytes. |
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| Dilutions: | Peptide ELISA 1:2000, Western Blot 1:1000, Immunohistochemistry 1:200 |
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| Unit Size: | 0.1 mg |
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| Concentration: | 0.5 mg/ml |
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| Positive Controls: | 2 Positive Controls |
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Packaging: | Storage: | Aliquot and store at -20 °C or -80 °C. Avoid freeze-thaw cycles. |
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| Buffer: | Tris saline [pH7.3] containing 0.5% BSA |
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| Preservative: | 0.02% Sodium Azide |
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| Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. |
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Background: Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells. ApoE is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. The APOE gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants.
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Images (2) Reviews (0) Related Products (29) Exploring ApoE Working with ApoE
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Jump to: Publications, Images, Ask a Question
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Working with ApoE
ApoE Antibody Images (2) Immunohistochemistry: APOE Antibody [NB100-1530]-(2.5ug/ml) staining of paraffin embedded Human Liver. Steamed antigen retrieval with citrate buffer pH 6, AP-staining. |  Western Blot: APOE Antibody [NB100-1530] (0.1ug/ml) staining of Human Brain lysate (35ug protein in RIPA buffer). |
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Publications (1)ApoE Antibody Product Specific:- Dodart JC, Marr RA, Koistinaho M, Gregersen BM, Malkani S, Verma IM, Paul SM. Gene delivery of human apolipoprotein E alters brain A{beta} burden in a mouse model of Alzheimer's disease. Proc Natl Acad Sci U S A. 2005 Jan 25;102(4):1211-6. Epub 2005 Jan 18.
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Jump to: Positive Controls, Lysates, Peptides and Proteins, Primary Antibodies, RNAi, Secondary Antibodies
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Related ProductsPositive ControlsLysates (1)Peptides and ProteinsPrimary Antibodies (12)| Name | Catalog# | Reactivity | Applications | Images | Publications | Reviews | |
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| ApoE Antibody (WUE-4) | NB110-60531 | Hu | ELISA, IHC, WB | (1) | (4) | | | | ApoE Antibody (EP1374Y) | NB110-55466 | Hu, Rt | ICC, IHC-P, IP, WB | (3) | (3) | | | | ApoE Antibody (EP1373Y) | NB110-55467 | Hu, Mu(-), Rt(-) | FACS, IHC-P, IP, WB | (2) | (3) | | | | ApoE Antibody | NB400-158 | Hu | ELISA, IHC-P, WB | | (1) | | | | ApoE Antibody | NB100-2040 | Mu | IHC-P, WB | | (1) | | | | ... and 7 more. See All » |
RNAi (1)Secondary Antibodies| Name | Catalog# | Reactivity | Applications | Images | Publications | Reviews | |
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| Goat IgG Antibody [FITC] | NB710-F | Gt | ICC, IHC-P | | | | | | Goat IgG Antibody [Biotin] | NB710-B | Gt | ELISA, ICC, IHC-P, WB | | | | | | Goat IgG Antibody [Alkaline Phosphatase] | NB710-AP | Gt | ELISA, ICC, IHC-P, WB | | | | | | Goat IgG Antibody [HRP] | NB710-H | Gt | ELISA, ICC, IHC-P, WB | | (4) | | | | Goat IgG Antibody [Cy3] | NB120-6949 | Gt | ELISA, FACS, ICC, IF, IHC-Fr, IHC-P | | | | | | See All » |
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