Apg3 Antibody (NB110-74780)
Apg3 Antibody
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anti-ATG3 antibody, anti-protein PC3-96 antibody, anti-MGC15201 antibody, anti-hApg3 antibody, anti-FLJ22125 antibody, anti-DKFZp564M1178 antibody, anti-APG3-like antibody, anti-APG3L antibody, anti-APG3 antibody, |
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Apg3 Antibody Summary: | | Gene: | ATG3 |
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| Purity: | Whole antisera |
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| Host: | Sheep |
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| | | Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur. |
View Additional Apg3 Products Apg3 Antibody Details: | Immunogen: | A synthetic peptide as a part of human, rat, mouse autophagy-related protein 3 (ATG3, APG3, APG3L, APG3-like, hApg3, protein PC3-96) conjugated to immunogenic carrier protein has been used as the immunogen. |
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Human, mouse and rat. Other species not yet tested. |
| Uses: | IHC-Paraffin/Frozen, WB 1 : 200 to 1 : 5000. The optimal dilution should be determined by the end user. |
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| Dilutions: | Immunohistochemistry-Frozen, Immunohistochemistry-Paraffin, Western Blot 1:200 to 1:5000 |
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| Unit Size: | 0.1 ml |
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| Concentration: | lyoph |
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| Positive Controls: | 1 Positive Controls |
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Packaging: | Storage: | Store at 4 °C short term. Aliquot and store at -20 °C long term. Avoid freeze-thaw cycles. |
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| Buffer: | Lyophilized Reconstitute in 0.1 ml of sterile water. Centrifuge to remove any insoluble material. When reconstituting, glycerol (1:1) may be added for an additional stability. |
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| Preservative: | No Preservative |
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| Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. |
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Background: Autophagy is a process of bulk degradation of cytoplasmic components by the lysosome or vacuole. Human ATG3 displays the same enzymatic characteristics in vitro as yeast Apg3, a protein-conjugating enzyme essential for autophagy. ; FUNCTION: GABARAPL1 (GABARAPL2 or GABARAP or MAP1LC3)-modifier protein conjugating enzyme involved in its E2-like covalent binding to PE. ATG7 (E1-like enzyme) facilitates this reaction by forming an E1-E2 complex with ATG3 (E2-like enzyme). Preferred substrate is MAP1LC3A. Formation of the GABARAPL1-PE conjugate is essential for autophagy. ; SUBCELLULAR LOCATION: Cytoplasm ; TISSUE SPECIFICITY: Widely expressed, with a highest expression in heart, skeletal muscle, kidney, liver and placenta.
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Reviews (0) Related Products (17) Exploring Apg3 Working with Apg3
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Working with Apg3
Apg3 Antibody Images (0)
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Publications (3)Apg3 Antibody Background References:- Tanida I, et al. J. Biol. Chem. 277 (16), 13739-13744(2002).
- Brill L.M, et al. Anal. Chem. 76 (10), 2763-2772(2004).
more... - Tanida I, et al. FEBS J. 273 (11), 2553-2562(2006).
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Jump to: Positive Controls, Lysates, Peptides and Proteins, Primary Antibodies, RNAi, Secondary Antibodies
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Related ProductsPositive ControlsLysates (1)Peptides and ProteinsPrimary Antibodies (12)| Name | Catalog# | Reactivity | Applications | Images | Publications | Reviews | |
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| Apg3 Antibody | R-159-100 | Hu, Rt | IF, IHC-P, WB | (4) | (1) | | | | Apg3 Antibody (EPR4801) | NBP1-95645 | Hu, Mu, Rt | ICC, IF, IHC-P, WB | (3) | | | | | Apg3 Antibody (EPR4802) | NBP1-95706 | Hu, Mu, Rt | ELISA, FACS, IP, WB | (2) | | | | | Apg3 Antibody | NBP1-77168 | Hu, Mu, Rt | ELISA, IHC-P, WB | (2) | | | | | Apg3 Antibody | PAB0740 | Hu, Rt | IF, IHC-Fr, WB | | | | | | ... and 7 more. See All » |
RNAi (1)Secondary Antibodies| Name | Catalog# | Reactivity | Applications | Images | Publications | Reviews | |
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| Sheep IgG Antibody [Texas Red] | NB7582 | Sh | FACS, FLISA, IF, IHC-Fr, IHC-P | | (1) | | | | Sheep IgG Antibody [Alkaline Phosphatase] | NB120-7112 | Sh | ELISA, IHC-Fr, IHC-P, WB | | (2) | | | | Sheep IgG Antibody [Rhodamine] | NB120-6744 | Sh | FACS, IF, IHC-Fr, IHC-P | | (1) | | | | Sheep IgG, H/L chains Antibody [DyLight 488] | NBP1-72996 | Sh | FLISA, IF, WB | (1) | | | | | Sheep IgG, H/L chains Antibody [DyLight 549] | NBP1-72997 | Sh | FLISA, IF, WB | (1) | | | | | See All » |
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