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Amyloid beta precursor protein Antibody (NBP1-35300)

Amyloid beta precursor protein Antibody

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Amyloid beta precursor protein Antibody Summary:
Species:Hu
Applications:IHC-P, WB
Clonality:Polyclonal
Gene:APP
Purity:Immunogen affinity purified
Host:Rabbit
Specificity:This product is specific for Amyloid b/Amyloid A4
 
Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur.
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Amyloid beta precursor protein Antibody Details:
Isotype:IgG
Immunogen:A synthetic peptide from N-terminus of human amyloid beta.
Species Reactivity:

This product is specific for Human.

Applications:
Uses:This product is useful for Immunohistochemistry Paraffin,Western Blot. This product has a prediluted size available. If a 6mL or 7mL pre-diluted size is purchased this product can be used Neat (without further dilution). Use recommended dilution for the concentrated vials only.
Dilutions:Immunohistochemistry-Paraffin 1:100, Western Blot
Unit Size:0.1 ml (also available: 0.5 ml, 1.0 ml, 7.0 ml)
Concentration:Please see the vial label for concentration.
Notes:
This product has a prediluted size available. If a 6mL or 7mL pre-diluted size is purchased this product can be used Neat (without further dilution). Use recommended dilution for the concentrated vials only.
Packaging:
Storage:Store at 4 °C. Do not freeze.
Buffer:10mM PBS, pH 7.4
Preservative:Sodium Azide
Limitations:This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months.
Gene Symbol: APP
Entrez351 (Human)
 
Background:

The cerebral and vascular plaques associated with Alzheimer's disease (AD) are mainly composed of amyloid beta peptides (Ab). Ab is derived from cleavage of the amyloid precursor protein (APP) and varies in length from 39 to 43 amino acids. Ab [1-40], Ab [1-42], and Ab [1-43] peptides result from cleavage of APP after residues 40, 42, and 43, respectively. The cleavage takes place by gamma secretase during the last APP processing step. Ab [1-40], [1-42] and [1-43] peptides are major constituents of the plaques and tangles that occur in AD. Ab antibodies and peptides have been developed as tools for elucidating the biology of AD.
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