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Amyloid Precursor Protein Antibody (NB120-2072)

Amyloid Precursor Protein Antibody

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Amyloid Precursor Protein Antibody Summary:
Species:Hu, Mu, Rt
Applications:WB
Clonality:Polyclonal
Gene:APP
Purity:Immunogen affinity purified
Host:Rabbit
Specificity:Amyloid Precursor Protein
Publications:Antibody has at least 2 Background References.
Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur.
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Amyloid Precursor Protein Antibody Details:
Isotype:IgG
Immunogen:Peptide sequence corresponding to amino acids 653 to 662 of human amyloid A4 protein precursor (APP). Identical to that of rabbit, pig, bovine, guinea pig and chicken.
Localization:Endoplasmic reticulum, Golgi Apparatus, Cytoplasmic, Cell Membrane.
Epitope:DAEFRHDSGY
Species Reactivity:

Cross-reacts with Human, Rat and Mouse. Not yet tested in other species.

Applications:
Uses:Western blot (1:500 to 1:1000) for detection of APP and Ab peptide.
Dilutions:Western Blot 1:500-1:1000
Unit Size:0.05 mg
Concentration:Please see the vial label for concentration.
Positive Controls:2 Positive Controls
Packaging:
Storage:Aliquot and store at -20 °C or -80 °C. Avoid freeze-thaw cycles.
Buffer:PBS
Preservative:0.02% Sodium Azide
Limitations:This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months.
Gene Symbol: APP
Entrez351 (Human)
29722 (Rat)
 
Images (2)
  • Western Blot: Amyloid Precursor Protein Antibody [NB120-2072] - Western blot analysis of APP in human (A), mouse (B), and rat (C) brain tissue lysates with anti-APP at 1 ìg/ml.
  • Immunohistochemistry: Amyloid Precursor Protein Antibody [NB120-2072] - Immunohistochemistry of APP in human brain (Alzheimer's disease) tissue with anti-APP at 10 ug/ml.

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2 Background References
Jump to: Publications, Images, Ask a Question

Working with Amyloid Precursor Protein

Amyloid Precursor Protein Antibody Images (2)
Western Blot: Amyloid Precursor Protein Antibody [NB120-2072] - Western blot analysis of APP in human (A), mouse (B), and rat (C) brain tissue lysates with anti-APP at 1 ìg/ml.Immunohistochemistry: Amyloid Precursor Protein Antibody [NB120-2072] - Immunohistochemistry of APP in human brain (Alzheimer's disease) tissue with anti-APP at 10 ug/ml.
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Publications (2)

Amyloid Precursor Protein Antibody Background References:

  1. Ponte P et al. A new A4 amyloid mRNA contains a domain homologous to serine proteinase inhibitors. Nature 331:525-7 (1988).
  2. Selkoe DJ Cell biology of the amyloid beta-protein precursor the mechanism of Alzheimer's disease. Annu Rev Cell Biol 10:373-403 (1994).
Protocols
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Jump to: Positive Controls, Primary Antibodies, Secondary Antibodies

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Try our bioinformatic tool that shows the relationships between APP and other genes, diseases, pathways and post-translational modifications.