Adiponectin/Acrp30 Antibody

Adiponectin is a 28 kD is a complement 1q family member that is involved in the control of fat metabolism and insulin sensitivity. Adiponectin forms multimers, under non-reducing, non-heat denaturing conditions with approximate molecular weights of gt300 kD, 167 kD, and 67 kD. Under reducing conditions with no heat, adiponectin is approximately 67 kD; under reducing conditions with heat, the adiponectin monomer has an apparent molecular weight of approximately 28 kD. Adiponectin can be modified by glycosylation and hydroxylation. Adiponectin is synthesized and secreted into plasma by adipocytes. Adiponectin has also been shown to act as a negative regulator of hematopoiesis and inflammation. In macrophages and endothelial cells adiponectin has been shown to downregulate TNF-induced adhesion molecules, and block NF- kappaB signaling though a cAMP-dependent mechanism. Decreased levels of adiponectin are associated with obesity insulin resistance and type 2 diabetes. IL-6 inhibits adiponectin production and secretion. Adiponectin has been shown to interact with collagen type I, III, and V. The Poly6215 antibody has been shown to be useful for Western blotting of human adiponectin.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Array NB100-78417

• Adiponectin/Acrp30 Antibodies
• Adiponectin/Acrp30 ELISA Kits
• Adiponectin/Acrp30 Lysate
• Adiponectin/Acrp30 Proteins
• Adiponectin/Acrp30 ELISAs
• Adiponectin/Acrp30 Proteins and Enzymes