Adenovirus Antibody (NB120-3648)

Adenovirus Antibody (M58 + M73)

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Adenovirus Antibody (M58 + M73) Summary:
Species:Vi
Applications:IHC-Fr, IHC-P
Clonality:Monoclonal
Purity:IgG purified
Host:Mouse
Specificity:This antibody reacts with adenovirus. Adenovirus early gene product E1A is a potent stimulator of cellular proliferation. When overexpressed, it can overcome the growth-inhibitory effects of TGF-beta. The E1A region encodes a series of related proteins (35-46 kD) with multifunctional capabilities and forms a specific complex with the retinoblastoma tumor suppressor gene product. The E1A and E1B regions together comprise the transforming region of adenovirus. While expression of E1A alone is sufficient to immortalize primary cells, complete transformation requires the additional expression of the E1B region.
Publications:Antibody has at least 3 Background References.
Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur.
View Additional Adenovirus Products
Adenovirus Antibody (M58 + M73) Details:
Clone:M58 + M73
Isotype:IgG2a Kappa
Immunogen:Adenovirus.
Localization:Nuclear.
Species Reactivity:

Virus.

Applications:
Uses:Immunohistochemistry (formalin fixed paraffin embedded / frozen sections): use at a dliution of 1/50 - 1/75 in an ABC method.Not tested in other applications.Optimal dilutions / concentrations should be determined by the end user.Formalin fixed paraffin embedded tissue sections require high temperature antigen unmasking with 10 mM citrate buffer, pH 6.0 prior to immunostaining.
Dilutions:Immunohistochemistry-Frozen, Immunohistochemistry-Paraffin,
Unit Size:0.5 ml
Concentration:Please see the vial label for concentration.
Positive Controls:1 Positive Controls
Packaging:
Storage:Store at 4 °C. Do not freeze.
Buffer:Liquid
Preservative:Sodium Azide
Limitations:This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months.
Background:

The adenovirus early gene products E1A is a potent stimulator of cellular proliferation, which when overexpressed can overcome the growth inhibitory effects of TGF beta. The E1A region encodes a series of related proteins (35 - 46 kD) with multifunctional capabilities and forms a specific complex with the retinoblastoma tumor suppressor gene product. The E1a and E1B regions together comprise the transforming region of adenovirus. While expression of E1A alone is sufficient to immortalize primary cells, complete transformation requires the additional expression of the E1B region.

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Working with Adenovirus

Adenovirus Antibody (M58 + M73) Images (1)
Immunohistochemistry:Adenovirus Antibody (M58 + M73)[NB120-3648]- Formalin fixed paraffin embedded human infected appendix stained with Adenovirus antibody
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Publications (3)

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Jump to: Positive Controls, Primary Antibodies, Secondary Antibodies

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  • Suitable tissue control sections for Immunohistochemistry:Adenovirus infected tissue.
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Secondary Antibodies
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Mouse IgG Antibody [Biotin]NB720-BMuELISA, IHC-P, WB

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Mouse IgG Antibody [Alkaline Phosphatase]NB720-APMuELISA, ICC, IHC-P, WB

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Mouse IgG AntibodyNB120-7056Bv(-), Ch(-), Eq(-), Gp(-), Gt(-), Ha(-), Hu(-), Mu, Rb(-), Rt(-), Sh(-)ELISA, IHC-P, IP, WB

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Adenovirus in Context


Research Areas related to Adenovirus (1):
Adenovirus in the News (1):