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Alpha Actinin (pan) Antibody

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Product Details

Summary
Product Discontinued
View other related Alpha Actinin (pan) Primary Antibodies

Order Details


    • Catalog Number
      NBP1-19535
    • Availability
      Product Discontinued

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Alpha Actinin (pan) Antibody Summary

Immunogen
Synthetic peptide, corresponding to amino acids 30-70 of Human Actinin-alpha2.
Specificity
Recognizes both alpha-actinin-2 and alpha-actinin-3. Alpha-actinin-2 (Gene ID: 59, UniProt: P62736); Alpha-actinin-3 (Gene ID: 89, UniProt: Q08043).
Clonality
Polyclonal
Host
Rabbit
Gene
ACTN1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 1:50-1:200
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:50-1:200
  • Western Blot 1:500-1:1000
Theoretical MW
103 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Human, Mouse, Rat

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2)
Preservative
0.05% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Alpha Actinin (pan) Antibody

  • actinin 1 smooth muscle
  • actinin, alpha 1
  • alpha-actinin 1
  • Alpha-actinin cytoskeletal isoform
  • alpha-actinin-1
  • F-actin cross-linking protein
  • FLJ40884
  • FLJ54432
  • Non-muscle alpha-actinin-1

Background

Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins,including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple rolesin different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles andadherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, andsmooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillaractin filaments.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Additional Alpha Actinin (pan) Products

Array NBP1-19535

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Bioinformatics

Gene Symbol ACTN1