Actin Alpha 2 Smooth Muscle Antibody (NBP1-22788)

Actin Alpha 2 Smooth Muscle Antibody (1A4)

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Actin Alpha 2 Smooth Muscle Antibody (1A4) Summary:
Species:Hu
Applications:IHC, IHC-P
Clonality:Monoclonal
Gene:ACTA2
Purity:IgG purified
Host:Mouse
Specificity:This is specific to alpha-smooth isoform of actin. It reacts with smooth muscle cells of vessels and different parenchymes. This does not cross-react with beta and gamma-cytoplasmic, alpha-sarcomeric and alpha-myocardial actin isoforms.
Publications:Antibody has at least 1 Background Reference.
Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur.
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Actin Alpha 2 Smooth Muscle Antibody (1A4) Details:
Clone:1A4
Isotype:IgG2a Kappa
Immunogen:BALB/C mice were injected with N-terminal decapeptide of alpha-smooth muscle actin.
Localization:Cytoplasmic
Species Reactivity:

Human.

Applications:
Uses:This antibody has been pretitered and quality controlled to work on formalin-fixed paraffin-embedded and acetone fixed cryostat tissue sections. No further titration is required.
Dilutions:immunohistochemistry , Immunohistochemistry-Paraffin
Unit Size:6.0 ml
Concentration:Please see the vial label for concentration.
Positive Controls:1 Positive Controls
Packaging:
Storage:Store at 4 °C. Do not freeze.
Preservative:No Preservative
Limitations:This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months.
Gene Symbol: ACTA2
 
Background:

Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. In vertebrates 3 main groups of actin isoforms, alpha, beta and gamma have been identified. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins coexist in most cell types as components of the cytoskeleton and as mediators of internal cell motility. This antibody reacts with smooth muscle cells of blood vessels and parenchymal tissue of intestine, testis and ovary.

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Publications (1)

Actin Alpha 2 Smooth Muscle Antibody (1A4) Background References:

  1. 1) Skalli et al. Am J Cell Biol 103: 2787, 1986.2) Skalli et al. Lab Invest 60: 275, 1989.3) Skalli et al. J Histo Chem 37: 315, 1989.

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Jump to: Positive Controls, Lysates, Peptides and Proteins, Primary Antibodies, RNAi, Secondary Antibodies

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Positive Controls
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Lysates (2)
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Actin Alpha 2 Smooth Muscle LysateNBL1-07272WB(1)

Actin Alpha 2 Smooth Muscle LysateH00000059-T02WB

Peptides and Proteins
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Actin Alpha 2 Smooth Muscle Recombinant ProteinH00000059-P01HuELISA, WB(1)

Primary Antibodies (12)
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Actin Alpha 2 Smooth Muscle AntibodyNB600-531Bb, Bv, Ch, Hu, Mu, Po, Rb, RtELISA, IHC-P, WB(1)(3)

Actin Alpha 2 Smooth Muscle Antibody (1A4)NB600-536Bb, Hu, Mk, Mu, Rb, RtELISA, ICC, IF, IHC-P, WB(1)(3)

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RNAi (1)
NameCatalog#ReactivityApplicationsImagesPublicationsReviews
Actin Alpha 2 Smooth Muscle RNAiH00000059-R01Hu(1)(4)

Secondary Antibodies
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Mouse IgG Antibody [Biotin]NB720-BMuELISA, IHC-P, WB

Mouse IgG Antibody [HRP]NB720-HMuELISA, ICC, IHC-P, WB

Mouse IgG Antibody [Alkaline Phosphatase]NB720-APMuELISA, ICC, IHC-P, WB

Mouse IgG Antibody [FITC]NB720-FMuICC, IHC-P(2)

Mouse IgG AntibodyNB120-7056Bv(-), Ch(-), Eq(-), Gp(-), Gt(-), Ha(-), Hu(-), Mu, Rb(-), Rt(-), Sh(-)ELISA, IHC-P, IP, WB

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