Acetylcholinesterase Antibody (NBP1-05146)
Acetylcholinesterase Antibody
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anti-Acetylcholine acetylhydrolase antibody, anti-Yt blood group antibody, Anti-YT antibody, Anti-N ACHE antibody, anti-ARACHE antibody, anti-Apoptosis related acetylcholinesterase antibody, Anti-ACHE protein antibody, anti-ACHE antibody, anti-Acetylcholinesterase YT blood group antibody, anti-Acetylcholinesterase antibody |
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Acetylcholinesterase Antibody Summary: | | Gene: | ACHE |
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| Purity: | Protein A purified |
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| Host: | Mouse |
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| | Specificity: | Specific for brain AChE and does not recognize AChE from erythrocytes. The can thus distinguish between mammalian brain AChE and erythrocyte AChE. Weak cross-reactivity with Torpedo marmorata AChE but none with AChE from electric eel or human BtChE. |
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| Publications: | Antibody has at least 4 Background References. |
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| | Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur. |
View Additional Acetylcholinesterase Products Acetylcholinesterase Antibody Details: | Isotype: | IgG1 Kappa |
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| Immunogen: | C-terminal 10 residues of brain acetylcholinesterase (human and bovine), absent from the erythrocyte enzyme. |
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| Marker: | Early Neuronal Development Marker |
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| Epitope: | C-terminal 10 residues (aa 574-583) of brain acetylcholinesterase (DS-AChE and SS-AChE) (1). |
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| Uses: | ELISA and Western Blot |
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| Dilutions: | ELISA 1:16000,
Western Blot 1:75, |
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| Unit Size: | 0.125 mg |
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| Concentration: | 1.0 mg/ml |
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Packaging: | Storage: | Store at 4 °C. Do not freeze. |
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| Buffer: | 0.01 M phosphate buffer, pH 7.4, with 0.5 M NaCl |
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| Preservative: | 15mM Sodium Azide |
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| Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. |
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Background: Acetylcholinesterase (AChE, EC.3.1.1.7.) is an enzyme located in the postsynaptic membrane and in the muscle endplates, where it hydrolyses the neurotransmitter acetylcholin. AChE from brain is a tetramer (G4-AChE) with a molecular mass of 320 kDa, AChE from erythrocytes is a dimer (G2-AChE) with a molecular mass of 170 kDa. Detection of higher levels of AChE in amniotic fluid can indicate fetal malformations such as neural tube defects.
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Publications (4)Acetylcholinesterase Antibody Background References:- Sorensen K, Gentinetta R, Brodbeck U (1982) An amphiphile-dependent form of human brain caudate nucleus acetylcholinesterase: purification properties. J Neurochem 39:1050-1060.
- Aziz-Aloya R, Sternfeld M, Soreq H (1993) Promoter elements alternative splicing in the human ACHE gene. Prog Brain Res 98:147-153.
more... - Rasmussen AG, Arends J, Larsen SO (1989) Evaluation quality control of a monoclonal antibody based enzyme antigen immunoassay of acetylcholinesterase in amniotic fluid. Sc J Clin Lab Invest 49:503-11.
- Boschetti N, Brodbeck U, Jensen SP, Koch C, Norgaard-Pedersen B (1996) Monoclonal antibodies against a C-terminal peptide of human brain acetylcholinesterase distinguish between erythrocyte brain acetylcholinestrases. Clin Chem 42:19-23.
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Related ProductsLysates (2)Peptides and ProteinsPrimary Antibodies (16)| Name | Catalog# | Reactivity | Applications | Images | Publications | Reviews | |
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| Acetylcholinesterase Antibody | NBP1-86844 | Hu | IF, IHC-P, WB | (2) | | | | | Acetylcholinesterase Antibody | NBP1-51274 | Hu, Mu, Rt | IHC-P, WB | (2) | | | | | Acetylcholinesterase Antibody | NBP1-77762 | Ba | ELISA, IP, WB | (1) | | | | | Acetylcholinesterase Antibody | NBP1-31329 | Hu | IF, WB | (2) | | | | | Acetylcholinesterase Antibody (HR2) | NB300-528 | Bv, Fe, Hu, Rb | ELISA, IHC-Fr, IP | | (2) | | | | ... and 11 more. See All » |
RNAi (2)Secondary Antibodies| Name | Catalog# | Reactivity | Applications | Images | Publications | Reviews | |
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| Mouse IgG Antibody [Biotin] | NB720-B | Mu | ELISA, IHC-P, WB | | | | | | Mouse IgG Antibody [HRP] | NB720-H | Mu | ELISA, ICC, IHC-P, WB | | | | | | Mouse IgG Antibody [Alkaline Phosphatase] | NB720-AP | Mu | ELISA, ICC, IHC-P, WB | | | | | | Mouse IgG Antibody [FITC] | NB720-F | Mu | ICC, IHC-P | | (2) | | | | Mouse IgG Antibody | NB120-7056 | Bv(-), Ch(-), Eq(-), Gp(-), Gt(-), Ha(-), Hu(-), Mu, Rb(-), Rt(-), Sh(-) | ELISA, IHC-P, IP, WB | | | | | | See All » |
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