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Datasheet
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Support & Research
ATR Antibody Summary
Immunogen
The immunogen recognized by this antibody maps to a region between residues 1675 and 1725 of human Ataxia Telangiectasia and Rad3-related using the numbering given in entry NP_001175.1 (GeneID 545).
Localization
Nuclear
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
ATR
Purity
Immunogen affinity purified
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301 kDa. Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Publications
Read Publications using NB100-322 in the following applications:
This anitbody can be used as the primary antibody in a PLA assay with the following as secondary antibodies: NB100-305, NB100-55324, NB100-1803, NB100-224, NB100-41429, NB100-381, NB100-464, NB100-2241, NB500-158, NB100-2350, NB100-204, NB100-206, NB110-40543
Alternate Names for ATR Antibody
ataxia telangiectasia and Rad3 related
Ataxia telangiectasia and Rad3-related protein
ATR
EC 2.7.11.1
FRAP-related protein 1
FRP1
FRP1FRAP-related protein-1
MEC1
protein kinase ATR
Rad3 related protein
SCKL1
SCKLMEC1, mitosis entry checkpoint 1, homolog
serine/threonine-protein kinase ATR
Background
Ataxia and Rad3-related protein kinase (ATR) is a direct upstream activator of Chk1. This suggests that ATR plays a role in sensing DNA damage and initiating a subsequent protein kinase cascade.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
The recent relationship of BRCA1 and 53BP1 The p53-binding protein 1 (53BP1) is a DNA damage response factor, which is recruited to nuclear structures at the site of DNA damage. DNA double-strand breaks (DSBs) are mutations that are detrimental to cell viability and genome stability, and m... Read full blog post.
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