ATG7 Antibody (NB110-74795)
ATG7 Antibody
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anti-ATG7 antibody, anti-ubiquitin-activating enzyme E1-like protein antibody, anti-hAGP7 antibody, anti-GSA7 antibody, anti-DKFZp434N0735 antibody, anti-APG7-like antibody, anti-APG7L antibody, |
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ATG7 Antibody Summary: | | Gene: | ATG7 |
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| Purity: | IgG purified |
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| Host: | Sheep |
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| | | Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur. |
View Additional ATG7 Products ATG7 Antibody Details: | Isotype: | IgG |
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| Immunogen: | A synthetic peptide as a part of human, rat, mouse autophagy-related protein 7 (ATG7, APG7-like, APG7L, hAGP7) conjugated to immunogenic carrier protein has been used as the immunogen. |
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Human, mouse and rat. Other species not yet tested. |
| Uses: | IHC-Paraffin/Frozen, WB. Use at a concentration of 1-10 |
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| Dilutions: | Immunohistochemistry-Frozen, Immunohistochemistry-Paraffin, Western Blot 1-10 ug/ml |
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| Unit Size: | 0.5 mg |
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| Concentration: | lyoph |
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| Positive Controls: | 1 Positive Controls |
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Packaging: | Storage: | Store at 4 °C short term. Aliquot and store at -20 °C long term. Avoid freeze-thaw cycles. |
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| Buffer: | Lyophilized in PBS Reconstitute in .5 ml of sterile water. Centrifuge to remove any insoluble material. |
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| Preservative: | No Preservative |
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| Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. |
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Background: This gene was identified based on homology to Pichia pastoris GSA7 and Saccharomyces cerevisiae APG7. In the yeast, the protein appears to be required for fusion of peroxisomal and vaculuolar membranes. The protein shows homlogy to the ATP-binding and catalytic sites of the E1 ubiquitin activating enzymes.; FUNCTION: Functions as an E1 enzyme essential for multisubstrates such as GABARAPL1 and ATG12. Forms intermediate conjugates with GABARAPL1 (GABARAPL2, GABARAP or MAP1ALC3). Formation of the final GABARAPL1-PE conjugate is essential for autophagy.; SUBUNIT: Homodimer. Interacts with ATG3 and ATG12. The complex, composed of ATG3 and ATG7, plays a role in the conjugation of ATG12 to ATG5.; SUBCELLULAR LOCATION: Cytoplasm.; TISSUE SPECIFICITY: Widely expressed, especially in kidney, liver, lymph nodes and bone marrow.; DOMAIN: The C-terminal part of the protein is essential for the dimerization and interaction with ATG3 and ATG12.
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Reviews (0) Related Products (26) Exploring ATG7 Working with ATG7
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Jump to: Publications, Ask a Question
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Working with ATG7
ATG7 Antibody Images (0)
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Publications (6)ATG7 Antibody Background References:- Yuan W, et al. Mol. Biol. Cell 10 (5), 1353-1366(1999).
- Tanida I, et al. Biochem. Biophys. Res. Commun. 292 (1), 256-262(2002).
more... - Tanida I, et al. J. Biol. Chem. 277 (16), 13739-13744(2002).
- Mizushima N, et al. FEBS Lett. 532 (3), 450-454(2002).
- Nemoto T, et al. J. Biol. Chem. 278 (41), 39517-39526(2003).
- Tanida I, et al. FEBS J. 273 (11), 2553-2562(2006).
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Jump to: Positive Controls, Lysates, Peptides and Proteins, Primary Antibodies, Secondary Antibodies
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Related ProductsPositive ControlsLysates (3)Peptides and ProteinsPrimary Antibodies (14)| Name | Catalog# | Reactivity | Applications | Images | Publications | Reviews | |
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| ATG7 Antibody | R-161-100 | Hu, Rt | IF, IHC-P | (3) | (11) | | | | ATG7 Antibody (EP1759Y) | NB110-55474 | Hu, Mu(-), Rt(-) | FACS, ICC, IHC-P, IP, WB | (2) | (3) | | | | ATG7 Antibody | NB600-1274 | Hu | ELISA, IF, WB | | (3) | | | | Atg7 Antibody (EPR6251) | NBP1-95872 | Hu, Mu, Rt | ICC, IF, WB | (2) | | | | | ATG7 Antibody | NBP1-89042 | Hu | IF, IHC-P, WB | (2) | | | | | ... and 9 more. See All » |
Secondary Antibodies| Name | Catalog# | Reactivity | Applications | Images | Publications | Reviews | |
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| Sheep IgG Antibody [Texas Red] | NB7582 | Sh | FACS, FLISA, IF, IHC-Fr, IHC-P | | (1) | | | | Sheep IgG Antibody [Alkaline Phosphatase] | NB120-7112 | Sh | ELISA, IHC-Fr, IHC-P, WB | | (2) | | | | Sheep IgG Antibody [Rhodamine] | NB120-6744 | Sh | FACS, IF, IHC-Fr, IHC-P | | (1) | | | | Sheep IgG, H/L chains Antibody [DyLight 488] | NBP1-72996 | Sh | FLISA, IF, WB | (1) | | | | | Sheep IgG, H/L chains Antibody [DyLight 549] | NBP1-72997 | Sh | FLISA, IF, WB | (1) | | | | | See All » |
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