ATG5 Antibody (R-138-500)
ATG5 Antibody
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Distributor Data...
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anti-Autophagy protein 5 antibody, biosensis. GENE NAME: ATG5 antibody, anti-ASP antibody, anti-Apoptosis-specific protein, anti-APG5-like antibody, anti-APG5L antibody, anti-APG5 antibody, anti-APG 5 antibody, |
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ATG5 Antibody Summary: | | Gene: | ATG5 |
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| Purity: | Immunogen affinity purified |
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| Host: | Rabbit |
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| | Specificity: | IHC and wb confirmed the specificity for APG5. |
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| Publications: | Antibody has been mentioned in at least 1 Publication. |
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| | Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur. |
View Additional ATG5 Products ATG5 Antibody Details: | Isotype: | IgG |
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| Immunogen: | A synthetic peptide corresponding to the C-terminal of human APG-5L. No immunogenic carrier protein was conjugated to the immunogen. Instead, Adjukine B (see the Adjuvants in biosensis' product list) has been used to orchestrate/boost the immune response. |
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| Localization: | Accession Number: ATG5_HUMAN |
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Human, not yet tested in other species. |
| Uses: | IHC-P, immunofluorescence, WB. A dilution of 1:200 to 1:1000 dilution is recommended for these applications. The optimal working dilution should be determined by the end user. |
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| Dilutions: | Immunofluorescence, Immunohistochemistry-Paraffin, Western Blot |
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| Unit Size: | 0.5 mg |
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| Concentration: | Lyoph |
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| Positive Controls: | 1 Positive Controls |
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Packaging: | Storage: | Store at 4 °C short term. Aliquot and store at -20 °C long term. Avoid freeze-thaw cycles. |
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| Buffer: | Lyophilized. Add diH20 to desired concentration. |
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| Preservative: | No Preservative |
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| Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. |
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Background: Autophagy is an important mechanism for nonselective intracellular breakdown whereby cytosol and organelles are encapsulated in vesicles, which are then engulfed and digested by lytic vacuoles/lysosomes. ATG5 is required for autophagy. It conjugates to ATG12 and associates with isolation membrane to form autophagosomes. The conjugate detaches from the membrane immediately before or after autophagosome formation is completed. Conjugation to ATG12 is essential for autophagy, but is not required for association with isolation membrane. ATG5 also plays an important role in the apoptotic process. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity.
This product is distributed on behalf of Biosensis Pty. Ltd. of Australia.
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Reviews (0) Related Products (33) Exploring ATG5 Working with ATG5
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Working with ATG5
ATG5 Antibody Images (0)
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Publications (1)ATG5 Antibody Product Specific:- Mizushima, N et al. (2003) Int J Biochem Cell Biol. 35(5), 553-61 ;
2. Baehrecke EH. Nat Rev Mol Cell Biol. 6(6):505-10. (2005) ;
3. Lum JJ, et al. Nat Rev Mol Cell Biol. 6(6):439-48. (2005) ;
4. Greenberg JT. Dev Cell. 8(6):799-801. (2005)
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Jump to: Positive Controls, Lysates, Peptides and Proteins, Primary Antibodies, RNAi, Secondary Antibodies
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Related ProductsPositive ControlsLysates (1)Peptides and ProteinsPrimary Antibodies (27)| Name | Catalog# | Reactivity | Applications | Images | Publications | Reviews | |
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| ATG5 Antibody | NB110-53818 | Bv, Hu, Mk, Mu, Po, Rt, Xp, Ze | IF, IHC-P, WB | (3) | (9) | | | | ATG5 Antibody | R-111-100 | Hu | IF, IHC-P, WB | (3) | (2) | | | | ATG5 Antibody | NBP1-76866 | Hu, Mu, Rt | ELISA, IHC-P, WB | (2) | | | | | ATG5 Antibody | NBP1-76992 | Hu, Mu, Rt | ELISA, IHC-P, WB | (2) | | | | | ATG5 Antibody | NB300-368 | Hu, Mu, Rt | ICC, IP, WB | (1) | (10) | | | | ... and 22 more. See All » |
RNAi (1)Secondary Antibodies| Name | Catalog# | Reactivity | Applications | Images | Publications | Reviews | |
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| Rabbit IgG Antibody [HRP] | NB730-H | Rb | ELISA, ICC, IHC-P, WB | | (5) | | | | Rabbit IgG Antibody [FITC] | NB730-F | Rb | ICC, IHC-P | | (1) | | | | Rabbit IgG Antibody [Biotin] | NB730-B | Rb | ELISA, ICC, IHC-P, WB | | | | | | Rabbit IgG, H/L Chains Antibody [DyLight 488] | NBP1-72944 | Rb | FLISA, IF, WB | (3) | | | | | Rabbit IgG Antibody [Alkaline Phosphatase] | NB730-AP | Rb | ELISA, ICC, IHC-P, WB | | (1) | | | | See All » |
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