ATG5 Antibody (NB110-53818C)
ATG5 Antibody [DyLight 650]
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anti-hCG_32959 antibody, anti-Homolog of S Cerevisiae autophagy 5 antibody, anti-ATG5 autophagy related 5 homolog antibody, anti-APG 5L antibody, anti-Autophagy protein 5 antibody, anti-OTTHUMP00000040507 antibody, anti-hAPG5 antibody, anti-ATG5 autophagy related 5-like antibody, anti-ATG5 autophagy related 5 homolog (S. cerevisiae) antibody, anti-ATG5 antibody, anti-ATG 5 antibody, anti-ASP antibody, anti-apoptosis-specific protein antibody, anti-apoptosis specific protein antibody, anti-APG5-like antibody, anti-APG5L antibody, anti-APG 5 antibody, |
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ATG5 Antibody [DyLight 650] Summary: | | Gene: | ATG5 |
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| Purity: | Peptide affinity purified |
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| Host: | Rabbit |
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| | Specificity: | This is selective for the full-length and calpain cleaved isoform proteins. The short isoform is missing a.a. 1-79. The calpain cleaved form of ATG5 is missing a.a. 195-275. |
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| Publications: | Antibody has been mentioned in at least 3 Publications. |
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| | Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur. |
View Additional ATG5 Products ATG5 Antibody [DyLight 650] Details: | Conjugate: | DyLight 650 |
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| Immunogen: | A synthetic peptide made to an N-terminal region (within residues 1-50) of the human ATG5 protein. [Swiss-Prot# Q9H1Y0] |
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| Localization: | Cytoplasm. Co-localizes with non-muscle actin. |
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Reacts with bovine, human, mouse, rat, cow, pig, primate, Xenopus and Zebrafish. |
| Uses: | This antibody is useful for Western blot analysis. The molecular weight of human ATG5 is ~33 kDa. |
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| Dilutions: | immunohistochemistry 2.5ug/ml,
Western Blot 1:500 |
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| Unit Size: | 0.1 ml |
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| Concentration: | 1.0 mg/ml |
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| Positive Controls: | 1 Positive Controls |
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| Conjugated Antibodies: | 4 Conjugated Antibodies |
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Packaging: | Storage: | Store at 4 °C. Do not freeze. |
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| Buffer: | 50mM sodium borate |
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| Preservative: | No Preservative |
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| Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. |
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Background: Autophagy is an important mechanism for nonselective intracellular breakdown whereby cytosol and organelles are encapsulated in vesicles, which are then engulfed and digested by lytic vacuoles/lysosomes. ATG5 is required for autophagy. It conjugates to ATG12 and associates with isolation membrane to form autophagosomes. The conjugate detaches from the membrane immediately before or after autophagosome formation is completed. Conjugation to ATG12 is essential for autophagy, but is not required for association with isolation membrane. ATG5 also plays an important role in the apoptotic process. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity.
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Reviews (0) Related Products (33) Exploring ATG5 Working with ATG5
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Working with ATG5
ATG5 Antibody [DyLight 650] Images (0)
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Publications (3)ATG5 Antibody [DyLight 650] Product Specific:- Cadwell K, Liu JY, Brown SL, et al. A key role for autophagy the autophagy gene Atg16l1 in mouse human intestinal Paneth cells. Nature 2008;456(7219):259-263.
- Pyo, J., Nah, J., Kim, H., et al. Compensatory activation of ERK1/2 in Atg5-deficient mouse embryo fibroblasts suppresses oxidative stress-induced cell death. Autophagy. April 2008; 4:3, 315-321.
more... - Wang, Y., R. Singh, et al. Loss of Macroautophagy Promotes or Prevents Fibroblast Apoptosis Depending on the Death Stimulus. J. Biol. Chem. 2008; 283: 4766-4777. (IF)
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Jump to: Conjugated Antibodies, Positive Controls, Lysates, Peptides and Proteins, Primary Antibodies, RNAi, Secondary Antibodies
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Related ProductsConjugated Antibodies| Name | Catalog# | Reactivity | Applications | Images | Publications | Reviews | |
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| ATG5 Antibody [HRP] | NB110-53818H | Bv, Hu, Mk, Mu, Po, Rt, Xp, Ze | ICC, IHC, WB | | (3) | | | | ATG5 Antibody [DyLight 488] | NB110-53818G | Bv, Hu, Mk, Mu, Po, Rt, Xp, Ze | IHC, WB | | (3) | | | | ATG5 Antibody [DyLight 550] | NB110-53818R | Bv, Hu, Mk, Mu, Po, Rt, Xp, Ze | IHC, WB | | (3) | | | | ATG5 Antibody [Biotin] | NB110-53818B | Bv, Hu, Mk, Mu, Po, Rt, Xp, Ze | IHC, WB | | (3) | | |
Positive Controls| Name | Catalog# | Reactivity | Applications | Images | Publications | Reviews | |
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Other Positive Controls- Mouse wildtype ES cell lysate
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Lysates (1)Peptides and ProteinsPrimary Antibodies (27)| Name | Catalog# | Reactivity | Applications | Images | Publications | Reviews | |
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| ATG5 Antibody | NB110-53818 | Bv, Hu, Mk, Mu, Po, Rt, Xp, Ze | IF, IHC-P, WB | (3) | (9) | | | | ATG5 Antibody | R-111-100 | Hu | IF, IHC-P, WB | (3) | (2) | | | | ATG5 Antibody | R-138-500 | Hu | IF, IHC-P, WB | | (1) | | | | ATG5 Antibody | NBP1-76866 | Hu, Mu, Rt | ELISA, IHC-P, WB | (2) | | | | | ATG5 Antibody | NBP1-76992 | Hu, Mu, Rt | ELISA, IHC-P, WB | (2) | | | | | ... and 22 more. See All » |
RNAi (1)Secondary Antibodies| Name | Catalog# | Reactivity | Applications | Images | Publications | Reviews | |
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| Rabbit IgG Antibody [HRP] | NB730-H | Rb | ELISA, ICC, IHC-P, WB | | (5) | | | | Rabbit IgG Antibody [FITC] | NB730-F | Rb | ICC, IHC-P | | (1) | | | | Rabbit IgG Antibody [Biotin] | NB730-B | Rb | ELISA, ICC, IHC-P, WB | | | | | | Rabbit IgG, H/L Chains Antibody [DyLight 488] | NBP1-72944 | Rb | FLISA, IF, WB | (3) | | | | | Rabbit IgG Antibody [Alkaline Phosphatase] | NB730-AP | Rb | ELISA, ICC, IHC-P, WB | | (1) | | | | See All » |
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