ATG4B Antibody (R-157-100)
ATG4B Antibody
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anti-Cysteine protease ATG4B antibody, biosensis. GENE NAME: ATG4B antibody, anti-KIAA0943 antibody, anti-hAPG4B antibody, anti-Autophagy-related protein 4 homolog B antibody, anti-Autophagy-related cysteine endopeptidase 1 antibody, anti-Autophagin-1 antibody, anti-AUT-like 1 cysteine endopeptidase, anti-AUTL1 antibody, anti-APG4B antibody, |
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ATG4B Antibody Summary: | | Gene: | ATG4B |
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| Purity: | IgG purified |
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| Host: | Rabbit |
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| | Specificity: | TISSUE SPECIFICITY: Mainly expressed in the skeletal muscle, followed by brain, heart, liver and pancreas. SIMILARITY: Belongs to the peptidase C54 family. |
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| Publications: | Antibody has been mentioned in at least 1 Publication. |
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| | Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur. |
View Additional ATG4B Products ATG4B Antibody Details: | Immunogen: | A synthetic peptide (CLERFFDSEDED) corresponding to the C-terminus of human ATG4B protein conjugated to Blue Carrier Protein has been used as the immunogen. The peptide is homologous with the corresponding sequence derived from of ATG4B protein in mouse and rat. |
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| Localization: | Accession Number: ATG4 B_HUMAN ; ATG4 B_MOUSE ; ATG4 B_RAT |
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Human, rat. Other species not yet tested. |
| Uses: | This antibody is useful for Western Blot, Immunofluorescence and Immunohistochemistry-P. |
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| Dilutions: | Immunofluorescence, Immunohistochemistry-Paraffin 1:1000-1:2000, Western Blot 1:1000-1:2000 |
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| TMW: | 44 kDa |
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| Unit Size: | 0.1 ml |
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| Concentration: | Lyoph |
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| Positive Controls: | 1 Positive Controls |
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Packaging: | Storage: | Store at 4 °C short term. Aliquot and store at -20 °C long term. Avoid freeze-thaw cycles. |
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| Buffer: | Lyophilized. Add diH20 to desired concentration. |
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| Preservative: | No Preservative |
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| Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. |
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Background: FUNCTION: Cysteine protease required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form (form II). Form II, with a revealed C-terminal glycine, is considered to be the phosphatidylethanolamine (PE)-conjugated form, and has the capacity for the binding to autophagosomes. ENZYME REGULATION: Inhibited by N-ethylmaleimide. SUBCELLULAR LOCATION: Cytoplasm (Probable). ALTERNATIVE PRODUCTS: 5 named isoforms produced by alternative splicing.
This product is distributed on behalf of Biosensis Pty. Ltd. of Australia.
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Images (2) Reviews (0) Related Products (8) Exploring ATG4B Working with ATG4B
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Jump to: Publications, Images, Ask a Question
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Working with ATG4B
ATG4B Antibody Images (2) Western Blot: ATG4B Antibody [R-157-100] - Western blot on Peripheral Blood Mononuclear Cells (PMBC) lysate using Rabbit antibody to ATG4B (APG4B): whole serum (R-157-100) at a dilution of 1:100 (ECL) |  Western Blot: ATG4B Antibody [R-157-100] - Western blot on 293 cell lysate using Rabbit antibody to ATG4B (APG4B): whole serum (R-157-100) at a dilution of 1:100. |
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Publications (1)ATG4B Antibody Product Specific:- Marino G, et al. J. Biol. Chem. 278:3671-3678(2003). ;
2. Kabeya Y, et al. J. Cell Sci. 117:2805-2812(2004). ;
3. Nagase T, et al. DNA Res. 6:63-70(1999). ;
4. Ota T, et al. Nat. Genet. 36:40-45(2004). ;
5. Sugawara K, et al. J. Biol. Chem. 280:40058-40065(2005). ;
6. Kumanomidou T, et al. J. Mol. Biol. 355:612-618(2006). ;
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Jump to: Positive Controls, Lysates, Peptides and Proteins, Primary Antibodies, Secondary Antibodies
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Related ProductsPositive ControlsLysates (1)Peptides and ProteinsPrimary Antibodies (3)Secondary Antibodies| Name | Catalog# | Reactivity | Applications | Images | Publications | Reviews | |
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