Reacts specifically with mouse 42 kDa ATF4 protein
Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur.
Synthetic peptide derived from N-terminal region of ATF4
Species Reactivity:
Human and Mouse.
Applications:
Uses:
This antibody is useful for Immunohistochemistry-Paraffin, Western Blot
Dilutions:
Immunohistochemistry-Paraffin 1:50 - 1:500, Western Blot 1:200 - 1:2000
TMW:
38.6 kDa
Unit Size:
0.2 ml
Concentration:
Lyoph
Packaging:
Storage:
Store at 4 °C short term. Aliquot and store at -20 °C long term. Avoid freeze-thaw cycles.
Buffer:
Lyophilized Ascites Rabbit antisera. Reconstitute in 200 ul of distilled water.
Preservative:
No Preservative
Limitations:
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months.
ATF4 is a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB2). The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain (referenced from Entrez gene)