ATF4 Antibody (NB100-81802)
ATF4 [phospho Ser245] Antibody
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anti-Activating Transcription Factor 4 antibody, anti-TXREB antibody, anti-TAXREB67 antibody, anti-Tax Responsive Enhancer Element B67 antibody, anti-DNA binding protein TAXREB67 antibody, anti-Cyclic AMP response element binding protein 2 antibody, anti-Cyclic AMP dependent transcription factor ATF 4 antibody, anti-CREB2 antibody, anti-CREB 2 antibody, anti-ATF4 protein antibody, anti-ATF 4 antibody, |
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ATF4 [phospho Ser245] Antibody Summary: | | Gene: | ATF4 |
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| Purity: | Immunogen affinity purified |
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| Host: | Rabbit |
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| | Specificity: | ATF4 (specific to Phospho-Ser245) detects endogenous levels of ATF4 only when phosphorylated at serine 245. |
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| Publications: | Antibody has at least 1 Background Reference. |
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| | Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur. |
View Additional ATF4 Products ATF4 [phospho Ser245] Antibody Details: | Isotype: | IgG |
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| Immunogen: | The antiserum was produced against synthesized phosphopeptide derived from human ATF4 around the phosphorylation site of serine 245 (N-R-SP-L-P). |
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| Modification: | phospho Ser245 |
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| Uses: | Immunohistochemistry-Paraffin |
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| Dilutions: | Immunohistochemistry-Paraffin 1:50-1:100 |
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| Unit Size: | 0.05 mg |
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| Concentration: | 1.0 mg/ml |
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| Positive Controls: | 1 Positive Controls |
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Packaging: | Storage: | Aliquot and store at -20 °C or -80 °C. Avoid freeze-thaw cycles. |
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| Buffer: | phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, and 50% glycerol. |
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| Preservative: | 0.02% Sodium Azide |
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| Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. |
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Background: ATF4 is a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB2). The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain (referenced from Entrez gene).
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Images (1) Reviews (0) Related Products (25) Working with ATF4
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Jump to: Publications, Images, Ask a Question
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Working with ATF4
ATF4 [phospho Ser245] Antibody Images (1) Immunohistochemistry: ATF4 Phosphospecific Antibody [NB100-81802] - Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue, using ATF4 (phospho-Ser245) antibody NB100-81802 |
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Publications (1)ATF4 [phospho Ser245] Antibody Background References:- Yang X, et al. (2004). Cell.117(3): 387-398.
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