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APE Antibody

 (2 Publications)
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Product Details

Summary
Product Discontinued
View other related APE Primary Antibodies

Order Details


    • Catalog Number
      NB100-474
    • Availability
      Product Discontinued

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APE Antibody Summary

Immunogen
Full length human APE1 purified from E. coli
Localization
Nuclear
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
APEX1
Purity
Unpurified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Western Blot
Application Notes
Predicted MW is 38 kDa.
Control
HeLa Whole Cell Lysate
APE Overexpression Lysate
Publications
Read Publications using NB100-474.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
Antiserum
Preservative
No Preservative
Purity
Unpurified

Alternate Names for APE Antibody

  • AP endonuclease 1
  • APE
  • APE1
  • APE-1
  • APEAPEX nuclease (multifunctional DNA repair enzyme)
  • APENAP endonuclease class I
  • APEX deoxyribonuclease (apurinic or apyrimidinic)
  • APEX nuclease (multifunctional DNA repair enzyme) 1
  • APEX nuclease
  • APEX1
  • Apurinic-apyrimidinic endonuclease 1
  • APXAP lyase
  • DNA-(apurinic or apyrimidinic site) lyase
  • EC 3.1
  • EC 4.2.99.18
  • HAP1apurinic/apyrimidinic (abasic) endonuclease
  • multifunctional DNA repair enzyme
  • protein REF-1
  • redox factor 1
  • Redox factor-1
  • REF1 apurinic/apyrimidinic exonuclease
  • REF-1

Background

Apurinic / apyrimidinic endonuclease (APE1 or REF1) is responsible for the incision of DNA basic sites during base excision repair. It has also been shown to stimulate the DNA binding activity of numerous transcription factors that are involved in cancer promotion and progression. Alterations in APE1 levels have been described in some cancers. APE1 is part of the cellular response to oxidative stress and protects cells from the genotoxic and cytotoxic effect of oxidizing agents.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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APE Antibody
NB100-474
APE Antibody
Species: Hu, Mu
Applications: WB

Publications for APE Antibody (NB100-474)(2)


Reviews for APE Antibody (NB100-474) (0)

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Product General Protocols

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Video Protocols

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FAQs for APE Antibody (NB100-474) (0)

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Control Lysate(s)

HeLa Whole Cell Lysate
APE Overexpression Lysate

Secondary Antibodies

 

Isotype Controls

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Research Areas for APE Antibody (NB100-474)

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Bioinformatics

Gene Symbol APEX1
Entrez