APE Antibody

Name: APE Antibody
Brand: Novus Biologicals
SKU: H00000328-B01
Price: 429 USD
Availability: Discontinued

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Summary

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Catalog Number

H00000328-B01
Availability

Product Discontinued

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APE Antibody Summary

Immunogen	APEX1 (NP_001632, 1 a.a. ~ 318 a.a) full-length human protein.
Specificity	APEX1 - APEX nuclease (multifunctional DNA repair enzyme) 1,
Clonality	Polyclonal
Host	Mouse
Gene	APEX1
Purity	Unpurified
Innovator's Reward	Test in a species/application not listed above to receive a full credit towards a future purchase. Learn about the Innovator's Reward

Applications/Dilutions

Dilutions	ELISA 1:100-1:2000 Immunocytochemistry/ Immunofluorescence 1:10-1:500 Immunohistochemistry 1:10-1:500 Immunohistochemistry-Paraffin 1:10-1:500 Western Blot 1:500
Application Notes	Antibody reactive against immunizing recombinant protein, transfected lysate and tissue lysate for Western Blot. Has also been used for immunofluoresence, and immunohistochemistry (paraffin sections), and ELISA.
Antagonist	APE1 Redox Inhibitor NBP1-49581

Packaging, Storage & Formulations

Storage	Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer	This is unpurified antiserum so it is not possible to supply the specific antibody concentration.
Preservative	No Preservative
Purity	Unpurified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for APE Antibody

AP endonuclease 1
APE
APE1
APE-1
APEAPEX nuclease (multifunctional DNA repair enzyme)
APENAP endonuclease class I
APEX deoxyribonuclease (apurinic or apyrimidinic)
APEX nuclease (multifunctional DNA repair enzyme) 1
APEX nuclease
APEX1
Apurinic-apyrimidinic endonuclease 1
APXAP lyase
DNA-(apurinic or apyrimidinic site) lyase
EC 3.1
EC 4.2.99.18
HAP1apurinic/apyrimidinic (abasic) endonuclease
multifunctional DNA repair enzyme
protein REF-1
redox factor 1
Redox factor-1
REF1 apurinic/apyrimidinic exonuclease
REF-1

Background

Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene; all encode the same protein.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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APE Antibody

H00000328-B01

Species: Hu

Applications: WB, ELISA, ICC/IF, IHC

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Bioinformatics

Gene Symbol	APEX1
Entrez	328(Human)
Uniprot	NP_001632(Human)

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Antibodies Secondary Antibodies Isotype Controls Proteins and Peptides ELISA Kits Sample Size New Products	About Us Careers Novus Guarantee Contact Us Our Team	Technical Support FAQs Protocols

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At	=	A. thaliana	SyHa	=	Golden Syrian Hamster
All	=	All Species	Ha	=	Hamster
An	=	Animal	Hu	=	Human
ArHa	=	Armenian Hamster	I	=	Insect
Av	=	Avian	Ll	=	Llama
Bb	=	Baboon	Ma	=	Mammal
Ba	=	Bacteria	Mk	=	Monkey
Bv	=	Bovine	Mu	=	Mouse
Ca	=	Canine	Multi	=	Multi-species
Ce	=	C. Elegans	NA	=	Non-species specific
Ch	=	Chicken	Or	=	Orangutan
ChHa	=	Chinese Hamster	Pl	=	Plant
Cm	=	Cynomolgus Monkey	Pm	=	Primate
Do	=	Donkey	Po	=	Porcine
Dr	=	Drosophilia	Rb	=	Rabbit
Ec	=	E. Coli	Rt	=	Rat
Eq	=	Equine	RM	=	Rhesus Macaque
Fe	=	Feline	Sh	=	Sheep
Ft	=	Ferret	Vb	=	Vertebrate
Fi	=	Fish	Vi	=	Virus
Fu	=	Fungi	Xp	=	Xenopus
Ge	=	Gerbil	Ye	=	Yeast
GP	=	Guinea Pig	Ze	=	Zebrafish
Gt	=	Goat

APE Antibody

Species Glossary

Images

Product Details

Order Details

APE Antibody Summary

Applications/Dilutions

Packaging, Storage & Formulations

Notes

Alternate Names for APE Antibody

Background

Limitations

Customers Who Viewed This Item Also Viewed...

Publications for APE Antibody (H00000328-B01) (0)

Reviews for APE Antibody (H00000328-B01) (0)

Product General Protocols

Video Protocols

FAQs for APE Antibody (H00000328-B01) (0)

Secondary Antibodies

Isotype Controls

Additional APE Products

Research Areas for APE Antibody (H00000328-B01)

Blogs on APE

Contact Information

Product PDFs

Calculators

Review this Product

Bioinformatics