ADAM23 Antibody (NB100-75282)
ADAM23 Antibody
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Distributor Data...
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anti-A disintegrin and metalloproteinase domain 23 antibody, anti-Metalloproteinase like disintegrin like and cysteine rich protein 3 antibody, anti-MDC 3 antibody, |
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ADAM23 Antibody Summary: | | Gene: | ADAM23 |
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| Purity: | Immunogen affinity purified |
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| Host: | Chicken |
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| | | Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur. |
View Additional ADAM23 Products ADAM23 Antibody Details: | Isotype: | IgY |
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| Immunogen: | The immunogen for this antibody was a sequence from 72a.a. to 144a.a. from ADAM 23(a 832a.a. long protein) |
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| Localization: | Nucleus. |
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This antibody is reactive against Human. |
| Uses: | Western Blot: E coli-derived fusion protein as test antigen. Affinity-purified IgY dilution: 1:2000. Goat anti-IgY-HRP dilution: 1:1000. Colorimetric method for signal development. |
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| Dilutions: | Western Blot |
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| Unit Size: | 0.05 mg |
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| Concentration: | Please see the vial label for concentration. |
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Packaging: | Storage: | Store at 4 °C short term. Aliquot and store at -20 °C long term. Avoid freeze-thaw cycles. |
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| Buffer: | Phosphate-Buffered Saline pH7.2 |
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| Preservative: | 0.02% Sodium Azide |
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| Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. |
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Background: ADAM23 is a non-catalytic metalloprotease-like protein. It is highly expressed in the brain, primarily in the amygdala, caudate nucleus, hypothalamus, thalamus, cerebral cortex and occipital pole, and weakly expressed in the heart. 3 isoforms are produced by alternative splicing, alpha, beta and gamma. ADAM23 may play a role in cell-cell and cell-matrix interactions.
May play a role in cell-cell and cell-matrix interactions. This is a non-catalytic metalloprotease-like protein.
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Images (1) Reviews (0) Related Products (4) Working with ADAM23
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Jump to: Publications, Images, Ask a Question
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Working with ADAM23
ADAM23 Antibody Images (1) Western Blot: E coli-derived fusion protein as test antigen. Affinity-purified IgY dilution: 1:2000, Goat anti-IgY-HRP dilution: 1:1000. Colorimetric method for signal development. ( anti-ADAM23 ) |
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Publications (8)ADAM23 Antibody Background References:- [8] , Sun Y.P., Deng K.J., Wang F., Zhang J., Huang X., Qiao S., Zhao S. Two novel isoforms of Adam23 expressed in the developmental process of mouse human brains.
- [7] , Cal S., Freije J.M.P., Lopez J.M., Takada Y., Lopez-Otin C. ADAM 23/MDC3, a human disintegrin that promotes cell adhesion via interaction with the alpha v beta 3 integrin through an RGD-independent mechanism.
more... - [6] , Sagane K., Ohya Y., Hasegawa Y., Tanaka I. Metalloproteinase-like, disintegrin-like, cysteine-rich proteins MDC2 MDC3: novel human cellular disintegrins highly expressed in the brain.
- [5] Roberts,C.M., Tani,P.H., Bridges,L.C., Laszik,Z. Bowditch,R.D., et al. MDC-L, a novel metalloprotease disintegrin cysteine-rich protein family member expressed by human lymphocytes
- [4] Cal,S., Freije,J.M., Lopez,J.M., Takada,Y. Lopez-Otin,C., et al. ADAM 23/MDC3, a human disintegrin that promotes cell adhesion via interaction with the alphavbeta3 integrin through an RGD-independent mechanism
- [3] Brenberger,R., Wei,H., Zhang,S., Lei,S., Murage,J., Fisk,G.J., Li,Y., Xu,C., Fang,R., Guegler,K., Rao,M.S., Malam,R.,, et al. Transcriptome characterization elucidates signaling networks that control human ES cell growth differentiation
- [2] Costa,F.F., Colin,C., Shinjo,S.M., Zanata,S.M., Marie,S.K., Sogayar,M.C. Camargo,A.A. ADAM23 methylation expression analysis in brain tumors
- [1] Takada,H., Imoto,I., Tsuda,H., Nakanishi,Y., Ichikura,T., Mochizuki,H., Mitsufuji,S., Hosoda,F., Hirohashi,S., Ohki,M. , et al. ADAM23, a possible tumor suppressor gene, is frequently silenced in gastric cancers by homozygous deletion or aberrant promoter hypermethylation
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Jump to: Primary Antibodies, Secondary Antibodies
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Related ProductsPrimary Antibodies (4)Secondary Antibodies| Name | Catalog# | Reactivity | Applications | Images | Publications | Reviews | |
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| Chicken IgY Antibody [Cy2] | NB120-6960 | Ch | FACS, ICC, IF, IHC-Fr, IHC-P | | | | | | Chicken IgG, H/L Chains Antibody [DyLight 649] | NBP1-72815 | Ch | FLISA, IF, WB | (2) | | | | | Chicken IgG, H/L Chains Antibody [DyLight 680] | NBP1-72816 | Ch | FLISA, IF, WB | (2) | | | | | Chicken IgG, H/L Chains Antibody [DyLight 800] | NBP1-72817 | Ch | FLISA, IF, WB | (2) | | | | | Chicken IgG, H/L Chains Antibody [DyLight 488] | NBP1-72818 | Ch | FLISA, IF, WB | (2) | | | | | See All » |
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Novus Explorer for ADAM23 gene
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