ACTR1A Antibody (NB100-1423)
ACTR1A Antibody
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anti-actin related protein 1 antibody, anti-Centrosome associated actin homolog antibody, anti-ARP1 antibody, anti-Alpha Centractin antibody, anti-Actin RPV antibody, |
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ACTR1A Antibody Summary: | | Gene: | ACTR1A |
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| Purity: | Immunogen affinity purified |
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| Host: | Goat |
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| | Specificity: | This epitope was selected to minimise the chance of cross-reactivity with ACTR1B (YEEDGSRAIHRKT). |
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| Publications: | Antibody has at least 1 Background Reference. |
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| | Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur. |
View Additional ACTR1A Products ACTR1A Antibody Details: | Isotype: | IgG |
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| Immunogen: | Synthetic peptide: YEEDGARSIHRKT representing the C-terminus of the human protein (residues 363-375) according to NP_005727. |
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| Localization: | Cytoplasmic |
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| Uses: | This antibody is useful for Peptide ELISA and Western Blot. Approx. 45kDa band observed in Human Kidney lysates (calculated MW of 42.6kDa according to NP_005727.1). |
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| Dilutions: | Immunohistochemistry 1:200, Peptide ELISA 1:32000 |
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| Unit Size: | 0.1 mg |
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| Concentration: | 0.5 mg/ml |
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| Positive Controls: | 2 Positive Controls |
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Packaging: | Storage: | Aliquot and store at -20 °C or -80 °C. Avoid freeze-thaw cycles. |
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| Buffer: | Tris-saline (pH7.3) with 0.5% BSA |
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| Preservative: | 0.02% Sodium Azide |
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| Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. |
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Background: The actin-related protein ACTR1A, a member of the superfamily of actin-related proteins, is the major subunit of the dynactin complex, a key component of the cytoplasmic dynein motor machinery. The major components of the dynactin complex, consisting of at least ten polypeptides, include ACTR1A. ACTR1A, the most abundant subunit in the dynactin complex, is most similar to conventional actin (>50% amino acid identity). The dynactin complex has been shown to localize to multiple structures within the cell, including membrane organelles, the centrosome, spindle poles, and spindle pole microtubules during mitosis and prometaphase kinetochores. It regulates dyneinmediated vesicle movement on microtubules as well as spindle assembly and cell division. ACTR1A overexpression in cells results in aberrant spindle morphologies and cell cycle delay at prometaphase, suggesting a possible function of ACTR1A/dynactin complex in progression through the prometaphase of mitosis.
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Images (1) Reviews (0) Related Products (11) Working with ACTR1A
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Working with ACTR1A
ACTR1A Antibody Images (1) Western Blot: ARP1 homolog A Antibody [NB100-1423]- staining (2ug/ml) of human kidney lysate (RIPA buffer, 35ug total protein per lane). Primary incubated for 1 hour. |
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Publications (1)
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Jump to: Positive Controls, Lysates, Peptides and Proteins, Primary Antibodies, RNAi, Secondary Antibodies
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Related ProductsPositive ControlsLysates (2)Peptides and ProteinsPrimary Antibodies (6)RNAi (1)Secondary Antibodies| Name | Catalog# | Reactivity | Applications | Images | Publications | Reviews | |
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| Goat IgG Antibody [FITC] | NB710-F | Gt | ICC, IHC-P | | | | | | Goat IgG Antibody [Biotin] | NB710-B | Gt | ELISA, ICC, IHC-P, WB | | | | | | Goat IgG Antibody [Alkaline Phosphatase] | NB710-AP | Gt | ELISA, ICC, IHC-P, WB | | | | | | Goat IgG Antibody [HRP] | NB710-H | Gt | ELISA, ICC, IHC-P, WB | | (4) | | | | Goat IgG Antibody [Cy3] | NB120-6949 | Gt | ELISA, FACS, ICC, IF, IHC-Fr, IHC-P | | | | | | See All » |
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Novus Explorer for ACTR1A gene
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