ACTL7A Protein (H00010881-H01)
ACTL7A Protein
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Distributor Data...
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ACTL7A Protein Summary: | | Gene: | ACTL7A |
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| Purity: | Protein |
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| | | Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur. |
View Additional ACTL7A Products ACTL7A Protein Details: | Immunogen: | This protein is not active and should not be used for experiments requiring activity. |
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| Uses: | This antibody is useful for ELISA, Western Blot, Blocking/Neutralizing This product may contain endotoxins and is not suitable for use with live cells. |
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| Dilutions: | ELISA, Western Blot, Blocking/Neutralizing |
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| Unit Size: | 25 ug |
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| Concentration: | Please see the vial label for concentration. |
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Notes: This product is produced by and distributed for Abnova, a company based in Taiwan. Packaging: | Storage: | Store at -80 °C. Avoid freeze-thaw cycles. |
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| Buffer: | 100 mM Tris-HCl pH 8.0, 150 mM NaCl, 1 mM EDTA, and 2.5 mM desthiobiotin. |
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| Preservative: | No Preservative |
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| Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. |
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Background: The protein encoded by this gene is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene (ACTL7A), and related gene, ACTL7B, are intronless, and are located approximately 4 kb apart in a head-to-head orientation within the familial dysautonomia candidate region on 9q31. Based on mutational analysis of the ACTL7A gene in patients with this disorder, it was concluded that it is unlikely to be involved in the pathogenesis of dysautonomia. The ACTL7A gene is expressed in a wide variety of adult tissues, however, its exact function is not known. [provided by RefSeq]
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