ACP1 Antibody (NB100-56474)
ACP1 Antibody
|
This product is fully covered under the Novus guarantee+ Policy.
Click
here for details.
|
|
Distributor Data...
|
|
anti-Acid phosphatase 1 antibody, |
|
|
ACP1 Antibody Summary: | | Gene: | ACP1 |
|---|
| Purity: | Protein G purified |
|---|
| Host: | Rabbit |
|---|
| | Specificity: | The amino acid sequence used as immunogen is 100% homologous in human, 93% in dog and orangutan, 86% in chicken and 80% homologous in mouse and rat (isoform a). It is also 100% homologous in human ACP1 isoforms c and d. An uncharacterized 45 kD band is also seen and blocked by the immunizing peptide. |
|---|
| Publications: | Antibody has at least 3 Background References. |
|---|
| | Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur. |
View Additional ACP1 Products ACP1 Antibody Details: | Isotype: | IgG |
|---|
| Immunogen: | A portion of amino acids 50-100 of human ACP1 was used as the immunogen. |
|---|
| Uses: | Western Blot |
|---|
| Dilutions: | Western Blot 1-3 ug/ml |
|---|
| Unit Size: | 0.1 mg |
|---|
| Concentration: | 0.5 mg/ml |
|---|
| Positive Controls: | 3 Positive Controls |
|---|
|
Packaging: | Storage: | Store at 4 °C short term. Aliquot and store at -20 °C long term. Avoid freeze-thaw cycles. |
|---|
| Buffer: | PBS containing 0.2% gelatin |
|---|
| Preservative: | 0.05% Sodium Azide |
|---|
| Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. |
|---|
Background: Official Gene Symbol: ACP1 Gen Bank Accession Number: NP_009030 Gene ID: 52 (Human) Gene Map Locus: 2p25 (Human) ACP1 (E.C 3.1.3.2) is a unique member of Phosphotyrosine Protein phosphotase family of proteins. It is ubiquitously expressed acid phosphotase functioning as an acid phosphotase and a protein tyrosine phosphotase. ACP1 has a cysteine-based catalytic mechanism and hydrolyzes protein tyrosine phosphate to protein tyrosine and orthophosphate. Reports suggest a functional role of ACP1 in TCR signaling and control of cell-cell adhesion through regulation of cytoskeletion assembly.
|
Images (1) Reviews (0) Related Products (19) Exploring ACP1 Working with ACP1
|
Jump to: Publications, Images, Ask a Question
|
Working with ACP1
ACP1 Antibody Images (1) Western Blot: ACP1 Antibody [NB100-56474] - Western blot analysis of ACP1 in the 1) absence and 2) presence of immunizing peptide in human liver lysate using NB100-56474 at 1 ug/ml. |
|
|
|
Publications (3)ACP1 Antibody Background References:- Giannoni et.al JBC 278 (38) 36763-36776 (September 19, 2003)
- Bottini et.al 277 (27) 24220-24224 (July 5, 2002)
more... - Wo,Y.Y., McCormack,A.L., Shabanowitz,J., Hunt,D.F., Davis,J.P., Mitchell,G.L. Van Etten,R.L. Sequencing, cloning, expression of human red cell-type acid phosphatase, a cytoplasmic phosphotyrosyl protein phosphatase J. Biol. Chem. 267 (15), 10856-10865 (1992)
|
|
|
|
Ask a Scientist
Can't find an answer to your question about ACP1? Ask us by using live
chat or by submitting your questions below:
|
Jump to: Positive Controls, Lysates, Peptides and Proteins, Primary Antibodies, RNAi, Secondary Antibodies
|
Related ProductsPositive ControlsLysates (2)Peptides and ProteinsPrimary Antibodies (11)RNAi (3)Secondary Antibodies| Name | Catalog# | Reactivity | Applications | Images | Publications | Reviews | |
|---|
| Rabbit IgG Antibody [HRP] | NB730-H | Rb | ELISA, ICC, IHC-P, WB | | (5) | | | | Rabbit IgG Antibody [FITC] | NB730-F | Rb | ICC, IHC-P | | (1) | | | | Rabbit IgG, H/L Chains Antibody [DyLight 488] | NBP1-72944 | Rb | FLISA, IF, WB | (3) | | | | | Rabbit IgG Antibody [Biotin] | NB730-B | Rb | ELISA, ICC, IHC-P, WB | | | | | | Rabbit IgG Antibody [Alkaline Phosphatase] | NB730-AP | Rb | ELISA, ICC, IHC-P, WB | | (1) | | | | See All » |
|
|
