ACCN4 Lysate (NBL1-07233)

ACCN4 Lysate

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ACCN4 Lysate Summary:
Applications:WB
Gene:ACCN4
Purity:Protein
Specificity:Homo sapiens amiloride-sensitive cation channel 4, pituitary (ACCN4), transcript variant 2, mRNA.
 
Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur.
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ACCN4 Lysate Details:
Immunogen:The lysate was created in HEK293T cells, using plasmid ID RC203827 and based on accession number NM_182847. The protein contains a C-terminal DDK tag.
Epitope:C-terminal Myc/DDK
Lysate Details:
Type: OverexpressionLife Stage: Adult
Protein State: Native Tissue Condition: Normal
Sub-cellular Fraction: Whole
Applications:
Uses:This product is intended for use as a positive control in Western Blot. You will receive the lysate (100ug), and an empty vector negative control (100 ug).
Dilutions:Western Blot
TMW:69.9 kDa
Unit Size:0.1 mg
Concentration:1.0 mg/ml
Notes:
This product is manufactured by and sold under license from OriGene Technologies and its use is limited solely for research purposes. Please note that “1 mg/ml” refers to the total protein concentration and that the specific protein concentration is not determined at this time.
Packaging:
Storage:Store at -80 °C. Avoid freeze-thaw cycles.
Buffer:RIPA buffer
Limitations:This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months.
Gene Symbol: ACCN4
Entrez55515 (Human)
Swiss ProtNM_182847 (Human)
 
Background:

This gene belongs to the superfamily of acid-sensing ion channels, which are proton-gated, amiloride-sensitive sodium channels. These channels have been implicated in synaptic transmission, pain perception as well as mechanoperception. This gene is predominantly expressed in the pituitary gland, and was considered a candidate for paroxysmal dystonic choreoathetosis (PDC), a movement disorder, however, no correlation was found between mutations in this gene and PDC. Alternative splicing at this locus results in two transcript variants encoding different isoforms. [provided by RefSeq]. Transcript Variant: This variant (2) is missing an inframe coding exon present in transcript variant 1. This results in a shorter isoform (2) lacking a 19 aa segment, compared to isoform 1.

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ACCN4 Lysate Images (1)
Western Blot: ACCN4 Lysate [NBL1-07233] - Western Blot experiments. Left-Control; Right -Over-expression Lysate for ACCN4
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