ACCN1 Antibody (NBP1-30544)
ACCN1 Antibody
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anti-Amiloride-sensitive brain sodium channel antibody, anti-Amiloride-sensitive antibody, anti-sodium antibody, anti-MDEG antibody, anti-mammalian degenerin homolog antibody, anti-mammalian antibody, anti-ion antibody, anti-homolog antibody, anti-degenerin antibody, anti-channel antibody, anti-brain sodium channel 1 antibody, anti-brain Antibody, anti-BNC1 antibody, anti-BNaC1 antibody. anti-BNC1 antibody, anti-BNAC1 antibody, anti-ASIC2 antibody, anti-acid-sensing ion channel 2 antibody, anti-Acid-sensing antibody, anti-ACCN antibody, anti-2 antibody, anti-1 antibody |
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ACCN1 Antibody Summary: | | Gene: | ACCN1 |
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| Purity: | IgG purified |
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| Host: | Rabbit |
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| | Specificity: | Appears to be specific for ACCN1. |
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| | Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur. |
View Additional ACCN1 Products ACCN1 Antibody Details: | Isotype: | IgG |
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| Immunogen: | A synthetic peptide from the cytoplasmic domain of human amiloride sensitive cation channel 1, neuronal (ACCN1, ASIC2) conjugated to an immunogenic carrier protein was used as the immunogen. The antigen is homologous in monkey and shares 95% identity with |
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Human. Other species not yet tested. |
| Uses: | IHC-Paraffin/Frozen, WB. A concentration of 10-50 µg/ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications. |
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| Dilutions: | Immunohistochemistry-Frozen, Immunohistochemistry-Paraffin, Western Blot |
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| Unit Size: | 0.5 mg |
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| Concentration: | lyoph |
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Notes: Reconstitute in 500 ul of sterile water. Centrifuge to remove any insoluble material. Packaging: | Storage: | Store at 4 °C short term. Aliquot and store at -20 °C long term. Avoid freeze-thaw cycles. |
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| Buffer: | lyophilized |
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| Preservative: | No Preservative |
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| Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. |
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Background: ACCN1 is a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. ACCN1 may play a role in neurotransmission. In addition, a heteromeric association between ACCN1 and ACCN3 (variant 1) has been observed to co-assemble into proton-gated channels sensitive to gadolinium. FUNCTION: Cation channel with high affinity for sodium, which is gated by extracellular protons and inhibited by the diuretic amiloride. Also permeable for Li(+) and K(+). Generates a biphasic current with a fast inactivating and a slow sustained phase. Heteromeric channel assembly seems to modulate. SUBUNIT: Homotetramer or heterotetramer with other ASIC proteins (Probable). Interacts with STOM. Interacts with PRKCABP and ACCN3. SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein. Note=Localized at the plasma membrane of neurons, in the soma and punctated peripheral processes.
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Jump to: Lysates, Primary Antibodies, RNAi, Secondary Antibodies
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