ACCN1 Antibody (NB110-74733)
ACCN1 Antibody
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anti-Amiloride-sensitive brain sodium channel antibody, anti-MDEG antibody, anti-mammalian degenerin homolog antibody, anti-brain sodium channel 1 antibody, anti-BNaC1 antibody. anti-BNC1 antibody, anti-BNAC1 antibody, anti-ASIC2 antibody, anti-acid-sensing ion channel 2 antibody, anti-ACCN antibody, |
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ACCN1 Antibody Summary: | | Gene: | ACCN1 |
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| Purity: | Whole antisera |
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| Host: | Rabbit |
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| | | Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur. |
View Additional ACCN1 Products ACCN1 Antibody Details: | Immunogen: | A synthetic peptide as a part of human & monkey (macaca fascicularis) amiloride-sensitive cation channel 1 (ASIC1) conjugated to immunogenic carrier protein was used as the immunogen. |
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| Localization: | Cell Membrane; multi-pass membrane protein |
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| Uses: | Immunohistochemistry-Paraffin/Frozen and Western Blot |
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| Dilutions: | Immunohistochemistry-Frozen, Immunohistochemistry-Paraffin, Western Blot |
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| Unit Size: | 0.1 ml |
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| Concentration: | lyoph |
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| Positive Controls: | 1 Positive Controls |
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Notes: Reconstitute in 0.1 ml of sterile water. Centrifuge to remove any insoluble material. When reconstituting, glycerol (1:1) may be added for an additional stability. Packaging: | Storage: | Store at 4 °C short term. Aliquot and store at -20 °C long term. Avoid freeze-thaw cycles. |
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| Buffer: | Lyophilized |
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| Preservative: | No Preservative |
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| Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. |
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Background: ACCN1 is a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. ACCN1 may play a role in neurotransmission. In addition, a heteromeric association between ACCN1 and ACCN3 (variant 1) has been observed to co-assemble into proton-gated channels sensitive to gadolinium. FUNCTION: Cation channel with high affinity for sodium, which is gated by extracellular protons and inhibited by the diuretic amiloride. Also permeable for Li(+) and K(+). Generates a biphasic current with a fast inactivating and a slow sustained phase. Heteromeric channel assembly seems to modulate. SUBUNIT: Homotetramer or heterotetramer with other ASIC proteins (Probable). Interacts with STOM. Interacts with PRKCABP and ACCN3. SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein. Note=Localized at the plasma membrane of neurons, in the soma and punctated peripheral processes.
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Reviews (0) Related Products (4) Working with ACCN1
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Jump to: Publications, Ask a Question
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Working with ACCN1
ACCN1 Antibody Images (0)
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Publications (5)ACCN1 Antibody Background References:- Hruska-Hageman A.M, et al. Biochem. J. 361:443-450(2002).
- Babinski K, et al. J. Biol. Chem. 275:28519-28525(2000).
more... - Garcia-Anoveros J, et al. Proc. Natl. Acad. Sci. U.S.A. 94:1459-1464(1997).
- Waldmann R, et al. J. Biol. Chem. 271:10433-10436(1996).
- Price M.P, et al. J. Biol. Chem. 271:7879-7882(1996).
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Jump to: Positive Controls, Lysates, Primary Antibodies, RNAi, Secondary Antibodies
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Related ProductsPositive ControlsLysates (1)Primary Antibodies (1)RNAi (2)Secondary Antibodies| Name | Catalog# | Reactivity | Applications | Images | Publications | Reviews | |
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| Rabbit IgG Antibody [HRP] | NB730-H | Rb | ELISA, ICC, IHC-P, WB | | (5) | | | | Rabbit IgG Antibody [FITC] | NB730-F | Rb | ICC, IHC-P | | (1) | | | | Rabbit IgG Antibody [Biotin] | NB730-B | Rb | ELISA, ICC, IHC-P, WB | | | | | | Rabbit IgG Antibody [Alkaline Phosphatase] | NB730-AP | Rb | ELISA, ICC, IHC-P, WB | | (1) | | | | Rabbit IgG Antibody [Cy3] | NB120-6939 | Rb | ELISA, FACS, ICC, IF, IHC-Fr, IHC-P | | (1) | | | | See All » |
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