abi1 Antibody (EP3954) (NBP1-96074)

abi1 Antibody (EP3954) (NBP1-96074) (0.1 mL)

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	Catalog Number	NBP1-96074
	Size(s)	0.1 mL	Price:
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anti-e3B1 antibody, anti-NAP1BP antibody, anti-Nap1BP antibody, anti-Abelson interactor 1 antibody, anti-AblBP4 antibody, anti-SSH3BP1 antibody, anti-Abi-1 antibody, anti-Spectrin SH3 domain-binding protein 1 antibody, anti-nap1 binding protein antibody, anti-Nap1-binding protein antibody, anti-interactor protein AblBP4 antibody, anti-Eps8-binding protein antibody, anti-eps8 binding protein antibody, anti-Eps8 SH3 domain-binding protein antibody, anti-ablBP4 antibody, anti-Abl-binding protein 4 antibody, anti-Abl-interactor protein 1 long antibody, anti-spectrin SH3 domain binding protein 1 antibody, anti-abl interactor 1 antibody, anti-E3B1 antibody, anti-SSH3BP antibody, anti-ABI-1 antibody, anti-abl-interactor 1 antibody

abi1 Antibody (EP3954) Summary:

Species:	Hu	Gene:	ABI1
Applications:	WB, FACS, ICC, IP	Purity:	Tissue culture supernatant
Clonality:	Monoclonal	Host:	Rabbit
Publications:

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Lysates	Peptides and Proteins
Primary Antibodies
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abi1 Antibody (EP3954) Details:

Clone:	EP3954
Immunogen:	A phospho specific peptide corresponding to residues surrounding tyrosine 435 of human ABI1 was used as an immunogen. This antibody only detects ABI1 phosphorylated at tyrosine 435.

Species Reactivity:

Human. Species cross-reactivity is based on Western Blot analysis.

Applications:

Uses:	This product is useful in Western Blot,Immunocytochemistry,Flow Cytometry,Immunoprecipitation,
Dilutions:	Flow Cytometry 1:10 - 100, Immunocytochemistry 1:250 - 500, Immunoprecipitation 1:10 -100, Western Blot 1:10000 - 50000
Unit Size:	0.1 mL
Concentration:	This product is unpurified. Concentration is not relevant.

Packaging:

Storage:	Store at -20°C. Avoid freeze-thaw cycles.
Buffer:	Antibody buffer, sodium azide, glycerol, and BSA.
Preservative:	0.01% Sodium Azide
Limitations:	This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months.

Gene Symbol: ABI1

Entrez:	10006 (Human)
Uniprot:	Q8IZP0 (Human)

Related Genes:

Background:

ABI1 has been found to form a complex with EPS8 and SOS1, and is thought to be involved in the transduction of signals from Ras to Rac. In addition, this protein may play a role in the regulation of EGF-induced Erk pathway activation as well as cytoskeletal reorganization and EGFR signaling (1). In vitro, a trimeric complex of ABI1, EPS8 and SOS1 exhibits Rac specific guanine nucleotide exchange factor (GEF) activity and ABI1 seems to act as an adapter in the complex. It regulates ABL1/c-Abl-mediated phosphorylation of MENA, and widely expressed, with highest expression in brain (2).

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abi1 Antibody (EP3954) Images (1)

	Western Blot: abi1 Antibody (EP3954) [NBP1-96074] Jurkat cell lysates using anti-Phospho-ABI1 (pY435). Cells were either (A) untreated (B) treated with Pervanadate.