Jump to Information on ABCG8 Antibody (NB400-110R)
ABCG8 Antibody [DyLight 550] Summary
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Species
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Human, Mouse (Negative) |
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Tested Applications
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WB |
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Clonality
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Polyclonal |
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Host
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Rabbit |
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Gene
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ABCG8 |
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Purity
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Immunogen affinity purified |
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Specificity
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Specific for ABCG8. |
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|
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|
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|
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|
ABCG8 Antibody [DyLight 550] Details
| Conjugate |
DyLight 550 (A=562, E=576) |
| Immunogen |
A synthetic peptide from the N-terminal region of human ABCG8 protein. |
| Localization |
Integral membrane protein; multi-pass membrane protein |
Applications/Dilutions
Product PDFs
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Publications
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Controls & Support Products
Research Tools
Packaging, Storage & Formulations
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Storage
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Store at 4C in the dark. |
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Buffer
|
50mM sodium borate |
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Unit Size
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0.1ml |
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Concentration
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1.0 mg/ml |
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Preservative
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No Preservative |
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Limitations
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This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt. |
Bioinformatics
| Gene Symbol |
ABCG8 |
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Entrez
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Uniprot
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Alternate Names for ABCG8
- ATP-binding cassette sub-family G member 8
- ATP-binding cassette
- sub-family G (WHITE)
- member
- ATP-binding cassette
- sub-family G (WHITE)
- member
- GBD4ATP-binding cassette
- subfamily G
- member 8 sl
- MGC142217
- sterolin 2
- sterolin-2
- Sterolin-2
- STSL
Related Products by Gene
ABCG5,
ABCB6,
ABCA1,
NPC1L1,
ABCB4,
ABCB11,
CYP7A1,
LDLR,
LXR,
SCARB1,
ABCG1,
ABCC1,
APOA1,
HMGCR,
ATP-BINDING CASSETTE TRANSPORTER,
ABCC2,
SOAT2,
SREBF2,
NR1H4,
ABCC3
Background
ATP-binding cassette (ABC) transporter genes are involved in the regulation of the amount of dietary cholesterol retained in the body. ABCG8, expressed at high levels in the liver and intestine, normally cooperates with ABCG5 to limit intestinal absorption and promote biliary excretion of sterols. The mutated form of this transporter can lead to sterol accumulation and atherosclerosis or sitosterolemia, a rare autosomal recessive disorder, characterized by hyperabsorption of sterols and the inability to excrete sterols into bile.
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Product General Protocols
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Video Protocols
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FAQs for ABCG8 (0)
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Bioinformatics Tool for ABCG8
Discover related pathways, diseases and genes to ABCG8. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Diseases for ABCG8
Discover more about diseases related to ABCG8.
- Sitosterolemia
- Hypercholesterolemia
- Atherosclerosis
- Cholecystolithiasis
- Coronary Artery Disease
- Cardiovascular Diseases
- Xanthoma
- Hyperlipidemia
- Insulin Resistance
- Malignant Neoplasms
- Coronary Heart Disease
- Cholelithiasis
- Cholesterol Gallstones
- Heart Diseases
- Inflammation
- Diabetes Mellitus
- Obesity
- Cholestasis
- Arteriosclerosis
- Dyslipidemias
Pathways for ABCG8
View related products by pathway.
- Transport
- Excretion
- Secretion
- Cholesterol Transport
- Intestinal Cholesterol Absorption
- Cholesterol Homeostasis
- Cholesterol Efflux
- Intestinal Absorption
- Reverse Cholesterol Transport
- Gallstone Formation
- Sterol Transport
- Localization
- Lipid Homeostasis
- Lipid Transport
- Pathogenesis
- Regulation Of Intestinal Cholesterol Absorption
- Sterol Homeostasis
- Response To Statin
- Fatty Acid Transport
- Response To Cholesterol
Research Areas for ABCG8
Find related products by research area.
PTMs for ABCG8
Learn more about PTMs related to ABCG8.
- Glycosylation
- Oxidation
- Phosphorylation
- Methylation
- Deglycosylation
- Carboxylation
- Reduction
- Cleavage
- Acetylation
- Palmitoylation
Blogs on ABCG8
Check out the latest blog posts on ABCG8.
-Western Blot-NBP1-95209-img0002.jpg "Western Blot: ABCG5 Antibody (EPR6203) [NBP1-95209] (A) Ramos and (B) HepG2 cell lysates.")
-Western Blot-NBL1-09704-img0002.jpg "Western Blot: CYP7A1 Overexpression Lysate (Adult Normal) [NBL1-09704] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for CYP7A1.")
-Western-Blot-NB110-57162-img0005.jpg "Western Blot: LDL Receptor Antibody (EP1553Y) [NB110-57162] - Western blot on Rat's liver samples with NB110-57162 at a dilution of 1:1000")
-Immunocytochemistry-Immunofluorescence-NB110-57162-img0004.jpg "Immunocytochemistry/Immunofluorescence: LDL Receptor Antibody (EP1553Y) [NB110-57162] HEPG2 cells.")
-Western Blot-NB400-156-img0006.jpg "Western Blot: MRP1 Antibody (IU2H10) [NB400-156] - Vector-transfected HEK293 cells 2: MRP1-transfected cells, prep1 3: MRP1-transfected cells, prep2 (the lower band is a degradation product.")
-Immunocytochemistry-Immunofluorescence-NB400-156-img0007.jpg "Immunocytochemistry/Immunofluorescence: MRP1 Antibody (IU2H10) [NB400-156] - The MRP-1 antibody was tested in HeLa cells at a 1:50 dilution against Dylight 488 (Green). Alpha tubulin and nuclei were counterstained against Dylight 550 (Red) and DAPI (Blue), respectively.")
