ABCG8 Antibody [DyLight 550] 0.1 ml

ABCG8 NB400-110R

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Ordering Information: NB400-110R

Catalog NumberNB400-110R
  • FormDyLight 550
  • Formats
  • Size(s)0.1 ml
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ABCG8 Antibody [DyLight 550] Summary

 
Species Human, Mouse (Negative)
Tested Applications WB
Clonality Polyclonal
Host Rabbit
Gene ABCG8
Purity Immunogen affinity purified
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ABCG8 Antibody [DyLight 550] Details

 
Format DyLight 550 (A=562, E=576)
Immunogen A synthetic peptide from the N-terminal region of human ABCG8 protein. [UniProt# Q9H221]
Localization Integral membrane protein; multi-pass membrane protein

Species Reactivity

 
Human. Does not appear to react with mouse.

Applications/Dilutions

 
Dilutions
  • Western Blot 1:500
Application Notes

This ABCG8 antibody is useful for Western blot. The antibody does not appear to be applicable in immunohistochemistry.

Other Available
Formats
Biotin Labeled NB400-110B
DyLight 488 Labeled NB400-110G
DyLight 650 Labeled NB400-110C
HRP Labeled NB400-110H
Learn about Custom Antibody Labeling

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Controls & Support Products

Research Tools

View all ABCG8 Research Tools.

Packaging, Storage & Formulations

 
Storage Store at 4C in the dark.
Buffer 50mM sodium borate
Unit Size 0.1 ml
Concentration 1.0 mg/ml
Preservative No Preservative
Limitations This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

 
Gene Symbol ABCG8
Entrez
Uniprot

Alternate Names for ABCG8

 
  • Sterolin-2
  • STSL
  • sterolin-2
  • MGC142217
  • sterolin 2
  • ATP-binding cassette, sub-family G (WHITE), member 8 (sterolin 2)
  • GBD4ATP-binding cassette, subfamily G, member 8
  • ATP-binding cassette sub-family G member 8
  • ATP-binding cassette, sub-family G (WHITE), member 8

Related Products by Gene

Background

 
ATP-binding cassette (ABC) transporter genes are involved in the regulation of the amount of dietary cholesterol retained in the body. ABCG8, expressed at high levels in the liver and intestine, normally cooperates with ABCG5 to limit intestinal absorption and promote biliary excretion of sterols. The mutated form of this transporter can lead to sterol accumulation and atherosclerosis or sitosterolemia, a rare autosomal recessive disorder, characterized by hyperabsorption of sterols and the inability to excrete sterols into bile.