ABCG8 Antibody (1B10A5) 0.025 ml

ABCG8 NBP1-71706

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Ordering Information: NBP1-71706

Catalog NumberNBP1-71706
  • FormUnconjugated
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ABCG8 Antibody (1B10A5) Summary

 
Species Human, Mouse
Tested Applications WB, ICC/IF, IHC, IHC-P, IP
Clonality Monoclonal
Host Mouse
Gene ABCG8
Purity Protein G purified
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ABCG8 Antibody (1B10A5) Details

 
Clone 1B10A5
Isotype IgG
Immunogen Full length mouse ABCG8 [Swiss-Prot# Q9DBM0]
Localization Membrane; Multi-pass membrane protein

Species Reactivity

 
Mouse and human.
Publications Read Publications using NBP1-71706 in the following species:
 

Applications/Dilutions

 
Dilutions
  • Western Blot 1:1000
  • Immunocytochemistry/Immunofluorescence 1:100
  • Immunohistochemistry 1:100
  • Immunohistochemistry-Paraffin 1:100
  • Immunoprecipitation 25ug
Application Notes

This ABCG8 (clone 1B10A5) antibody is useful for Western blot, Immunoprecipitation, Immunocytochemistry/Immunofluorescence and Immunohistochemistry on paraffin-embedded sections.

Other Available
Formats
Alexa Fluor (R) 405 Labeled NBP1-71706AF405
Alexa Fluor (R) 488 Labeled NBP1-71706AF488
Alexa Fluor (R) 647 Labeled NBP1-71706AF647
Alexa Fluor (R) 700 Labeled NBP1-71706AF700
Biotin Labeled NBP1-71706B
DyLight 405 Labeled NBP1-71706V
DyLight 488 Labeled NBP1-71706G
DyLight 550 Labeled NBP1-71706R
DyLight 650 Labeled NBP1-71706C
FITC Labeled NBP1-71706F
HRP Labeled NBP1-71706H
Learn about Custom Antibody Labeling
Publications
Read publications using
NBP1-71706 in the following applications:
  • WB4publications
  • ICC/IF2publications
  • IP2publications

Product PDFs

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Publications

ABCG8 Antibody (NBP1-71706) has been mentioned in at least 5 publications.
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Protocols and FAQs

Controls & Support Products

Research Tools

View all ABCG8 Research Tools.

Packaging, Storage & Formulations

 
Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer Tris-glycine, 150 mM NaCl
Unit Size 0.025 ml (also available in 0.1 ml)
Concentration 1 mg/ml
Preservative 0.05% Sodium Azide
Limitations This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

 
Gene Symbol ABCG8
Entrez
Uniprot

Alternate Names for ABCG8

 
  • Sterolin-2
  • STSL
  • sterolin-2
  • MGC142217
  • sterolin 2
  • ATP-binding cassette, sub-family G (WHITE), member 8 (sterolin 2)
  • GBD4ATP-binding cassette, subfamily G, member 8
  • ATP-binding cassette sub-family G member 8
  • ATP-binding cassette, sub-family G (WHITE), member 8

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Background

 
Normal digestion is partially facilitated by the function of ABCG8 and its counterpart ABCG5, which together form a heterodimer which transports cholesterol out of the liver and into bile. Subsequently, cholesterol is eliminated from the bodies of healthy individuals. However, in cases of insulin resistance, this functionality is impaired, and digestion does not result in complete elimination of harmful cholesterol. Unsurprisingly, mutations in ABCG8 can lead to gallstone disease, biliary cancer, hypercholesterolemia and atherosclerosis. In studies related to diabetes, heart disease, and digestive cancers, ABCG8 is commonly assessed for normal expression, function and interaction with ABCG5.