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ABCG5 RNAi

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Product Details

Summary
Product Discontinued
View other related ABCG5 RNAi

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    • Catalog Number
      H00064240-R01
    • Availability
      Product Discontinued

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ABCG5 RNAi Summary

Specificity
ATP-binding cassette, sub-family G (WHITE), member 5 (sterolin 1) (ABCG5), mRNA
Gene
ABCG5

Applications/Dilutions

Dilutions
  • RNA Inhibition
  • RNAi sequence position
Application Notes
This RNAi causes protein knockdown.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
DEPC-treated Water

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for ABCG5 RNAi

  • ATP-binding cassette sub-family G member 5
  • ATP-binding cassette, sub-family G (WHITE), member 5
  • ATP-binding cassette, subfamily G, member 5
  • sterolin 1
  • sterolin-1
  • STSL

Background

Chimera RNA interference (chimera RNAi) is process by which small interfering RNA/DNA chimera triggers the destruction of mRNA for the original gene.  The discovery work, design, and application of chimera RNAi has been pioneered by Professor Kaoru Saigo and Dr. Kumiko Ui-Tei at the University of Tokyo.  Chimera RNAi has many advantages over the conventional siRNAs.  First, it has been demonstrated to have reliable knock-down for over 10,000 human genes.  Because the human genome is composed of an intricate, genetic network, chimera RNAi's unique design has successfully obviated the off-target effects including microRNA-based influence.  Another advantage of the chimera RNAi technology is its effectiveness at low concentrations (0.5nM to 5nM); only mRNA is destroyed so genomic genes are not affected.  Finally, having both the sense and anti-sense strands consisting RNA/DNA chimera, it offers much greater compound stability for streamlining in vitro and in vivo assays and applications while minimizing interferon induction and other adverse reactions.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. RNAi are guaranteed for 3 months from date of receipt.

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Publications for ABCG5 RNAi (H00064240-R01) (0)

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Additional ABCG5 Products

Array H00064240-R01

Research Areas for ABCG5 RNAi (H00064240-R01)

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Blogs on ABCG5.

ABCG8: Cholesterol's Fate
The ATP-binding cassette (ABC) transporter genes are key gatekeeper molecules that regulate the amount of dietary cholesterol retained by the body. They are a multifamily comprised of cAMP-dependent anion transporter cell membrane proteins that monito...  Read full blog post.

ABCG2: A Tumor Protector
ABCG2 is a member of the ATP-binding cassette (ABC) transporter superfamily. Among ABC transporters ABCG2 is particularly interesting for its potential role in protecting cancer stem cells and its complex oligomeric structure (1). The ABC transporters...  Read full blog post.

Exploring how ABCG8 Affects Heart Disease
The high prevalence of atherosclerosis in developed nations is not breaking news; it has been well established that heart disease is the leading cause of death in the United States, and it presents a major socioeconomic burden. Investigators across th...  Read full blog post.

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Bioinformatics

Gene Symbol ABCG5