ABCG2 Partial Recombinant Protein (H00009429-Q02)

ABCG2 Partial Recombinant Protein

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ABCG2 Partial Recombinant Protein Summary:
Species:Hu
Protein Type:Partial Protein
Applications:ELISA, WB
Gene:ABCG2
Specificity:ABCG2 (NP_004818.2, 156 a.a. - 266 a.a.) partial recombinant protein with a ~26kD N-terminal GST tag.
 
Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur.
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ABCG2 Partial Recombinant Protein Details:
Immunogen:This protein is not active and should not be used for experiments requiring activity.
Applications:
Uses:Useful in Western Blot and ELISA. This protein has not been tested for any functionality. This product may contain endotoxins and is not suitable for use with live cells.
Dilutions:ELISA, Western Blot
Unit Size:10 ug (also available: 25 ug)
Concentration:Please see the vial label for concentration.
Notes:
This product is produced by and distributed for Abnova, a company based in Taiwan.
Packaging:
Storage:Store at -80 °C. Avoid freeze-thaw cycles.
Buffer:50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Limitations:This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months.
Gene Symbol: ABCG2
Entrez9429 (Human)
Swiss ProtNP_004818.2 (Human)
 
Background:

The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue. [provided by RefSeq]

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