ABCG2 Antibody (NBP1-19758)
ABCG2 Antibody
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anti-ABCG2 antibody, Anti-MXR1 antibody, anti-MXR antibody, anti-MRX antibody, anti-MGC102821 antibody, Anti-EST157481 antibody, anti-CDw338 antibody, anti-BMDP antibody, anti-BCRP1 antibody, anti-BCRP antibody, anti-ABCP antibody, anti-ABC15 antibody, |
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ABCG2 Antibody Summary: | | Gene: | ABCG2 |
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| Purity: | Affinity purified |
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| Host: | Rabbit |
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| | | Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur. |
View Additional ABCG2 Products ABCG2 Antibody Details: | Immunogen: | Synthetic peptide corresponing to the residues surrounding Asparagine 338 of human ABCG2 |
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| Marker: | Hematopoietic Stem Cell Marker |
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| Uses: | This antibody is useful for Western Blot and Immunohistochemistry. Western blot analysis of ABCG2 (N338) antibody in extracts from HT-29 cells. Immunohistochemistry analyzes of ABCG2 (N338) antibody in paraffin-embedded human brain tissue. Purity is > 95% (by SDS-PAGE). |
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| Dilutions: | Immunohistochemistry-Paraffin 1:50-1:200, Western Blot 1:500-1:1000 |
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| TMW: | 72 kDa |
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| Unit Size: | 0.1 mg |
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| Concentration: | 1.0 mg/ml |
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Packaging: | Storage: | Store at 4 °C short term. Aliquot and store at -20 °C long term. Avoid freeze-thaw cycles. |
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| Buffer: | Phosphate buffered saline (PBS), approx. pH 7.2. |
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| Preservative: | 0.05% Sodium Azide |
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| Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. |
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Background: ATP-binding cassette (ABC) transporters are an evolutionarily conserved family
of proteins that catalyze the transport of molecules across extracellular and
intracellular membranes through the energy of ATP hydrolysis. The ABC halftransporter,
ABCG2, is also known as placenta-specific ABC transporter and
breast cancer resistance protein (BCRP1). ABCG2 confers resistance for a
variety of chemotherapeutic agents, including anthracyclines, mitoxantrone,
bisantrene and topotecan. Under normal conditions, ABCG2 may serve a protective
function by removing toxins from the cell, and plays an important role
in regulating stem cell differentiation. ABCG2 is responsible for the side
population (SP) phenotype and is widely expressed in a large variety of stem
cells, making it an important stem cell marker. ABCG2 may have N-linked
glycosylation and may dimerize in vivo. ABCG2 is abundantly expressed in
placenta, liver, intestine and stem cells.
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Images (2) Reviews (0) Related Products (31) Exploring ABCG2
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Working with ABCG2
ABCG2 Antibody Images (2) Immunohistochemistry: ABCG2 Antibody [NBP1-19758] - ABCG2 Antibody [NBP1-19758] - paraffin-embedded human brain tissue. |  Western Blot: ABCG2 Antibody [NBP1-19758] - extracts from HT-29 cells. |
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Jump to: Lysates, Peptides and Proteins, Primary Antibodies, RNAi, Secondary Antibodies
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