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ABCG2/CD338 Antibody

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 (1 Review)
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Product Details

Summary
Product Discontinued
View other related ABCG2/CD338 Primary Antibodies

Order Details


    • Catalog Number
      NBP1-19758
    • Availability
      Product Discontinued

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ABCG2/CD338 Antibody Summary

Immunogen
Synthetic peptide, corresponding to amino acids 302-356 of Human ABCG2.
Marker
Stem Cell Marker
Clonality
Polyclonal
Host
Rabbit
Gene
ABCG2
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:50-1:200
  • Western Blot 1:500-1:1000
Application Notes
Western blot (WB) analysis of ABCG2 (N338) pAb in extracts from HT-29 cells.
Immunohistochemistry (IHC) analyzes of ABCG2 (N338) pAb in paraffin-embedded human brain tissue.
Theoretical MW
72 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Reviewed Applications
Read 1 Review rated 5
using
NBP1-19758 in the following applications:
Publications
Read Publication using
NBP1-19758 in the following applications:

Reactivity Notes

Human,Mouse and Rat.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2)
Preservative
0.05% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for ABCG2/CD338 Antibody

  • ABC transporter
  • ABC15
  • ABCG2
  • ABCP
  • ABCPMGC102821
  • ATP-binding cassette sub-family G member 2
  • ATP-binding cassette transporter G2
  • ATP-binding cassette, sub-family G (WHITE), member 2
  • BCRP
  • BCRP1
  • BCRPMRX
  • BMDP
  • Breast cancer resistance protein
  • CD338 antigen
  • CD338
  • CDw338
  • EST157481
  • mitoxantrone resistance protein
  • Mitoxantrone resistance-associated protein
  • MXR
  • MXRMXR1
  • placenta specific MDR protein
  • Placenta-specific ATP-binding cassette transporter

Background

ATP-binding cassette (ABC) transporters are an evolutionarily conserved family of proteins that catalyze the transport of molecules across extracellular and intracellular membranes through the energy of ATP hydrolysis. The ABC halftransporter, ABCG2, is also known as placenta-specific ABC transporter and breast cancer resistance protein (BCRP1). ABCG2 confers resistance for a variety of chemotherapeutic agents, including anthracyclines, mitoxantrone, bisantrene and topotecan. Under normal conditions, ABCG2 may serve a protective function by removing toxins from the cell, and plays an important role in regulating stem cell differentiation. ABCG2 is responsible for the side population (SP) phenotype and is widely expressed in a large variety of stem cells, making it an important stem cell marker. ABCG2 may have N-linked glycosylation and may dimerize in vivo. ABCG2 is abundantly expressed in placenta, liver, intestine and stem cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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ABCG2/CD338
Antibody
NBP1-19758
ABCG2/CD338 Antibody
Species: Hu, Mu, Rt
Applications: WB, IHC

Publications for ABCG2/CD338 Antibody (NBP1-19758)(1)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: ICC/IF.


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ICC/IF
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Review for ABCG2/CD338 Antibody (NBP1-19758) (1) 51

Average Rating: 5
(Based on 1 review)
We have 1 review tested in 1 species: Human.

Reviews using NBP1-19758:
Filter by Applications
ICC
(1)
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Human
(1)
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Images Ratings Applications Species Date Details
  5
reviewed by:
Verified Customer
 ICC Human 12/23/2014
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Summary

ApplicationImmunocytochemistry
Sample TestedSee PMID 24174130
SpeciesHuman

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Recent Reviews

5
5
1
4
0
3
0
2
0
1
0
 
 Verified Customer
12/23/2014
Application: ICC
Species: Human
read this review

Bioinformatics

Gene Symbol ABCG2
Entrez
Uniprot