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ABCG2 Antibody (NB110-93511)

ABCG2 Antibody (MM0047-2J39)

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ABCG2 Antibody (MM0047-2J39) Summary:
Species:Hu
Applications:FACS, IHC-P
Clonality:Monoclonal
Gene:ABCG2
Purity:Protein G purified
Host:Mouse
Specificity:This was selected for its ability to detect human ABCG2 by flow cytometry and immunocytochemistry.
 
Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur.
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ABCG2 Antibody (MM0047-2J39) Details:
Clone:MM0047-2J39
Isotype:IgG2
Immunogen:human recombinant rHABCG2 protein
Marker:Hematopoietic Stem Cell Marker
Species Reactivity:

Human.

Applications:
Uses:Flow Cytometry and Immunohistochemistry-Paraffin
Dilutions:Flow Cytometry 1:100-1000, Immunohistochemistry-Paraffin 1:100-1000
Unit Size:0.01 mg
Concentration:lyoph
Positive Controls:1 Positive Controls
Packaging:
Storage:Store at -20 °C. Avoid freeze-thaw cycles.
Buffer:PBS - lyophilized - Reconstitute the antibody with 500 ul sterile PBS and the final concentration is 200 ug/ml.
Preservative:No Preservative
Limitations:This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months.
Gene Symbol: ABCG2
Entrez9429 (Human)
 
Background:

An ABC transporter. Allows efflux of Hoechst dye, a property that has been used to separate bone marrow side population cells, which express BCRP/ABCG2. Appears to play a major role in the multidrug resistance phenotype of a specific MCF-7 breast cancer cell line. When overexpressed, the transfected cells become resistant to mitoxantrone, daunorubicin and doxorubicin, display diminished intracellular accumulation of daunorubicin, and manifest an ATP-dependent increase in the efflux of rhodamine 123.
Images (1)
  • Immunohistochemistry: ABCG2 Antibody (MM0047-2J39) [NB110-93511] - Immunohistochemistry-Paraffin: ABCG2 Antibody (MM0047-2J39) [NB110-93511] - Normal Human Placenta Tissue

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ABCG2 Antibody (MM0047-2J39) Images (1)
Immunohistochemistry: ABCG2 Antibody (MM0047-2J39) [NB110-93511] - Immunohistochemistry-Paraffin: ABCG2 Antibody (MM0047-2J39) [NB110-93511] - Normal Human Placenta Tissue
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