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ABCD1 Overexpression Lysate (Denatured)

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Product Details

Summary
Product Discontinued
View other related ABCD1 Lysates

Order Details


    • Catalog Number
      H00000215-T01
    • Availability
      Product Discontinued

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ABCD1 Overexpression Lysate (Denatured) Summary

Description
Quality control test: Transient overexpression cell lysate was tested with Anti-ABCD1 antibody by Western Blots. Plasmid: pCMV-ABCD1 full-length
Gene
ABCD1

Applications/Dilutions

Dilutions
  • Western Blot

Packaging, Storage & Formulations

Storage
Store at -80C. Avoid freeze-thaw cycles.
Buffer
Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, and 0.01% Bromophenol blue).

Lysate Details for Array

Type
Overexpression
Protein State
Denatured

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for ABCD1 Overexpression Lysate (Denatured)

  • Adrenoleukodystrophy protein
  • ALDATP-binding cassette sub-family D member 1
  • ALDPadrenoleukodystrophy
  • AMNABC42
  • ATP-binding cassette, sub-family D (ALD), member 1

Background

ABCD1 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). ABCD1 is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. ABCD1 peroxisomal membrane protein is likely involved in the peroxisomal transport or catabolism of very long chain fatty acids. Defects in ABCD1 have been identified as the underlying cause of adrenoleukodystrophy, an X-chromosome recessively inherited demyelinating disorder of the nervous system.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Lysates are guaranteed for 6 months from date of receipt.

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Bioinformatics

Gene Symbol ABCD1