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ABCC10 Antibody

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Product Details

Summary
Product Discontinued
View other related ABCC10 Primary Antibodies

Order Details


    • Catalog Number
      NBP1-00934
    • Availability
      Product Discontinued

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ABCC10 Antibody Summary

Immunogen
Synthetic peptide, corresponding to amino acids 834-887 of Human MRP7.
Clonality
Polyclonal
Host
Rabbit
Gene
ABCC10
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:1000
Theoretical MW
162 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Human

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2)
Preservative
0.05% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for ABCC10 Antibody

  • ATP-binding cassette sub-family C member 10
  • ATP-binding cassette, sub-family C (CFTR/MRP), member 10
  • MRP7SIMRP7EST182763
  • multidrug resistance-associated protein 7

Background

The MRP family is represented by nine similar ABC transporters that have the ability to transport structurally diverse lipophilic anions and operate as chemical efflux pumps. MRP7 (multidrug resistance-associated protein 7, ATPbinding cassette sub-family C member 10) is a multi-pass membrane protein that belongs to the ABC transporter family (conjugate transporter subfamily). MRP7 is involved with the ATP-dependent transport of 17beta-estradiol-D-17-beta-glucuronide (E217betaG). MRP7 is also probably involved in cellular detoxification through its lipophilic anion extrusion capabilities. MRP7 contains two ABC transmembrane type 1 domains and two ABC transporter domains. MRP7 likely has three isoforms. Isoform 2 is the most widely expressed, while isoform 1 is predominately expressed in the spleen.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol ABCC10
Entrez
Uniprot