anti-ATP-binding cassette, Anti-abcb5beta antibody, sub-family B (MDR/TAP), sub-family B, member 5N: P-glycoprotein ABCB5 antibody, member 5 antibody, member 5, Anti-pglycoprotein abcb5 antibody, anti-EST422562 antibody, anti-ATP-binding cassette, Anti-atp binding cassette sub family b mdr tap member 5 antibody; Anti-atp binding cassette sub family b member 5 antibody, anti-ABCB5beta antibody, anti-ABCB5alpha antibody,
Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur.
This antibody is specific for the N Terminus Region of the target protein.
Species Reactivity:
Human.
Applications:
Uses:
This product has been QC tested in ELISA against recombinant protein only. The concentration for this product is lot dependent. Check product vial for current lot concentration. Typically concentration ranges from 0.5 to 1.5 mg/ml.
Dilutions:
Western Blot 1:5000-1:20000,ELISA
Unit Size:
0.05 mg
Concentration:
Please see the vial label for concentration.
Notes:
Manufactured by SDIX's proprietary Genomic Antibody Technology™. GAT FAQs.
Packaging:
Storage:
Store at -20 °C. Avoid freeze-thaw cycles.
Buffer:
20 mM Potassium Phosphate, 150 mM Sodium Chloride, pH 7.0
Preservative:
No Preservative
Limitations:
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months.
ATP-Binding Cassette proteins comprise a superfamily of transporters with a wide variety of substrates. ABCB5 is a novel member of the human P-glycoprotein family. It functions as a determinant of membrane potential and regulator of cell fusion in physiologic skin progenitor cells. Cell fusion is thought to contribute to tissue differentiation. ABCB5 is predominantly expressed in melanoma cells and is a novel molecular marker for a distinct subset of chemoresistant stem cell phenotype-expressing tumor cells among human epidermal melanocytes. It has been identified as a novel drug transporter in human malignant melanoma. ABCB5 is a rhodamine efflux transporter. This antibody product is intended to be used to confirm cellular localization and expression level of ABCB5.