Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur.
This antibody is specific for the N Terminus Region of the target protein.
Species Reactivity:
Human.
Applications:
Uses:
This product has been QC tested in ELISA against recombinant protein only. The concentration for this product is lot dependent. Check product vial for current lot concentration. Typically concentration ranges from 0.5 to 1.5 mg/ml.
Dilutions:
Western Blot 1:5000-1:20000,ELISA
Unit Size:
0.05 mg
Concentration:
Please see the vial label for concentration.
Notes:
Manufactured by SDIX's proprietary Genomic Antibody Technology™.GAT FAQs.
Packaging:
Storage:
Store at -20 °C. Avoid freeze-thaw cycles.
Buffer:
20 mM Potassium Phosphate, 150 mM Sodium Chloride, pH 7.0
Preservative:
No Preservative
Limitations:
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months.
ABCA3 plays an important role in the formation of pulmonary surfactant, probably by transporting lipids such as cholesterol.
Defects in ABCA3 are the cause of pulmonary surfactant metabolism dysfunction type 3 (SMDP3) [MIM:610921]; also called pulmonary alveolar proteinosis due to ABCA3 deficiency. A rare lung disorder due to impaired surfactant homeostasis. It is characterized by alveolar filling with floccular material that stains positive using the periodic acid-Schiff method and is derived from surfactant phospholipids and protein components. Excessive lipoproteins accumulation in the alveoli results in severe respiratory distress.