ABCA1 Antibody (NB100-2068R)
ABCA1 Antibody (HJ1) [DyLight 550]
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Distributor Data...
anti-ATP-binding cassette sub-family A (ABC1) member 1 antibody, anti-OTTHUMP00000021833 antibody, anti-MGC165011 antibody, anti-MGC164864 antibody, anti-Membrane bound antibody, anti-FLJ14958 antibody, anti-ATP binding cassette sub-family A member 1 antibody, anti-ATP binding cassette sub family A ABC1 member 1 antibody, anti-ATP binding cassette sub family A member 1 antibody, anti-ATP binding Cassette 1 antibody, anti-ABCA1 antibody, anti-ABCA 1 antibody, anti-TD antibody, anti-ABC 1 antibody, anti-TGD antibody, anti-HDLDT1 antibody, anti-Cholesterol Efflux Regulatory Protein antibody, anti-CERP antibody, anti-ATP-binding Cassette Transporter 1 antibody, anti-ATP-binding Cassette 1 antibody, anti-ABC-1 antibody, anti-ABC1 antibody, anti-ABC Transporter 1 antibody,
ABCA1 Antibody (HJ1) [DyLight 550] Summary:
Gene :ABCA1 Purity: Protein G purified Host: Mouse
Specificity: This is specific for ABCA1.
Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur.
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ABCA1 Antibody (HJ1) [DyLight 550] Details:
Conjugate: DyLight 550 Clone: HJ1 Immunogen: 50 kDa N-terminal extracellular loop of ABCA1 Marker: Astrocyte Marker
This antibody reacts with rat and mouse ABCA1 and low reactivity with human. Other species have not been tested.
Uses: NB 100-2068 may be used for Western Blot where a band representing ABCA1 is seen at ~220 kDa. Optimal dilutions should be determined by the end user. Dilutions: Western Blot 1:2000 Unit Size: 0.1 ml Concentration: Please see the vial label for concentration. Conjugated Antibodies: 4 Conjugated Antibodies
Packaging:
Storage: Store at 4 °C. Do not freeze. Buffer: 50mM sodium borate Preservative: No Preservative Limitations: This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months.
Background:
Mutations in the ABCA1 gene (ATP-binding cassette transporter 1) have been reported in Tangier disease (TD). TD is an autosomal recessive disorder characterized by an absence of plasma HDL, cholesterol ester depositing in the reticulo-endothelial system and deviations in cellular lipid trafficking. ABCA1 mediates the apo-A1 associated export of cholesterol and phospholipids from the cell. It is expressed on the plasma membrane and the Golgi complex, and is regulated by cholesterol flux. Regulation of the cholesterol flux between HDL and macrophages is competitive between ABCA1 and SR-BI.
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