ABCA1 Antibody (NB100-2068C)

ABCA1 Antibody (HJ1) [DyLight 650]

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ABCA1 Antibody (HJ1) [DyLight 650] Summary:
Species:Mu, Rt
Applications:WB
Clonality:Monoclonal
Gene:ABCA1
Purity:Protein G purified
Host:Mouse
Specificity:This is specific for ABCA1.
 
Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur.
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ABCA1 Antibody (HJ1) [DyLight 650] Details:
Conjugate:DyLight 650
Clone:HJ1
Immunogen:50 kDa N-terminal extracellular loop of ABCA1
Marker:Astrocyte Marker
Species Reactivity:

This antibody reacts with rat and mouse ABCA1 and low reactivity with human. Other species have not been tested.

Applications:
Uses:NB 100-2068 may be used for Western Blot where a band representing ABCA1 is seen at ~220 kDa. Optimal dilutions should be determined by the end user.
Dilutions:Western Blot 1:2000
Unit Size:0.1 ml
Concentration:Please see the vial label for concentration.
Conjugated Antibodies:4 Conjugated Antibodies
Packaging:
Storage:Store at 4 °C. Do not freeze.
Buffer:50mM sodium borate
Preservative:No Preservative
Limitations:This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months.
Gene Symbol: ABCA1
Entrez19 (Human)
 
Background:

Mutations in the ABCA1 gene (ATP-binding cassette transporter 1) have been reported in Tangier disease (TD). TD is an autosomal recessive disorder characterized by an absence of plasma HDL, cholesterol ester depositing in the reticulo-endothelial system and deviations in cellular lipid trafficking. ABCA1 mediates the apo-A1 associated export of cholesterol and phospholipids from the cell. It is expressed on the plasma membrane and the Golgi complex, and is regulated by cholesterol flux. Regulation of the cholesterol flux between HDL and macrophages is competitive between ABCA1 and SR-BI.

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Jump to: Conjugated Antibodies, Peptides and Proteins, Primary Antibodies, RNAi, Secondary Antibodies

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Research Areas related to ABCA1 (10):
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