ABCA1 Antibody (NB100-2068)
ABCA1 Antibody (HJ1) - Astrocyte Marker
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anti-ATP-binding cassette sub-family A (ABC1) member 1 antibody, anti-OTTHUMP00000021833 antibody, anti-MGC165011 antibody, anti-MGC164864 antibody, anti-Membrane bound antibody, anti-FLJ14958 antibody, anti-ATP binding cassette sub-family A member 1 antibody, anti-ATP binding cassette sub family A ABC1 member 1 antibody, anti-ATP binding cassette sub family A member 1 antibody, anti-ATP binding Cassette 1 antibody, anti-ABCA1 antibody, anti-ABCA 1 antibody, anti-TD antibody, anti-ABC 1 antibody, anti-TGD antibody, anti-HDLDT1 antibody, anti-Cholesterol Efflux Regulatory Protein antibody, anti-CERP antibody, anti-ATP-binding Cassette Transporter 1 antibody, anti-ATP-binding Cassette 1 antibody, anti-ABC-1 antibody, anti-ABC1 antibody, anti-ABC Transporter 1 antibody, |
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ABCA1 Antibody (HJ1) - Astrocyte Marker Summary: | | Gene: | ABCA1 |
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| Purity: | Protein G purified |
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| Host: | Mouse |
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| | Specificity: | This is specific for ABCA1. |
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| Publications: | Antibody has been mentioned in at least 4 Publications. |
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| | Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur. |
View Additional ABCA1 Products ABCA1 Antibody (HJ1) - Astrocyte Marker Details: | Clone: | HJ1 |
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| Immunogen: | 50 kDa N-terminal extracellular loop of ABCA1 |
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| Marker: | Astrocyte Marker |
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NB 100-2068 reacts with rat, mouse, and human ABCA1. Other species have not been tested. |
| Uses: | This ABCA1 antibody is useful for IHC-paraffin embedded sections and Western blot, where a band is seen ~250 kDa . Prior to immunostaining paraffin tissues, antigen retrieval with sodium citrate buffer (pH 6.0) is recommended. Optimal dilutions should be determined by the end user. |
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| Dilutions: | Immunohistochemistry-Paraffin 1:400, Western Blot 1:2000 |
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| Unit Size: | 0.1 ml (also available: 0.025 ml (sample size)) |
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| Concentration: | Please see the vial label for concentration. |
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| Positive Controls: | 2 Positive Controls |
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| Conjugated Antibodies: | 5 Conjugated Antibodies |
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Packaging: | Storage: | Store at 4 °C short term. Aliquot and store at -20 °C long term. Avoid freeze-thaw cycles. |
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| Buffer: | PBS containing protease inhibitors |
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| Preservative: | Sodium Azide |
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| Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. |
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Background: Mutations in the ABCA1 gene (ATP-binding cassette transporter 1) have been reported in Tangier disease (TD). TD is an autosomal recessive disorder characterized by an absence of plasma HDL, cholesterol ester depositing in the reticulo-endothelial system and deviations in cellular lipid trafficking. ABCA1 mediates the apo-A1 associated export of cholesterol and phospholipids from the cell. It is expressed on the plasma membrane and the Golgi complex, and is regulated by cholesterol flux. Regulation of the cholesterol flux between HDL and macrophages is competitive between ABCA1 and SR-BI.
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Images (2) Reviews (0) Related Products (25) Exploring ABCA1 Working with ABCA1
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Jump to: Publications, Images, Protocols/Procedures, Ask a Question
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Working with ABCA1
ABCA1 Antibody (HJ1) - Astrocyte Marker Images (2)---Astrocyte-Marker-Immunohistochemistry-NB100-2068-img0001.jpg "Immunohistochemistry: ABCA1 Antibody (HJ1) - Astrocyte Marker [NB100-2068] - IHC analysis of ABCA1 in human renal cancer using DAB with hematoxylin counterstain.") Immunohistochemistry: ABCA1 Antibody (HJ1) - Astrocyte Marker [NB100-2068] - IHC analysis of ABCA1 in human renal cancer using DAB with hematoxylin counterstain. |  Western Blot: ABCA1 Antibody [NB100-2068] - Detection of ABCA1 in wildtype liver tissue (in RIPA) Lane 1: KO mouse liver tissue. Lane 2: WT mouse liver tissue. |
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Publications (4)ABCA1 Antibody (HJ1) - Astrocyte Marker Product Specific:- Lu YH, Su MY, Huang HY, Lin-Li, Yuan CG. Protective effects of the citrus flavanones to PC12 cells against cytotoxicity induced by hydrogen peroxide. Neurosci Lett. 2010 Oct 22;484(1):6-11. Epub 2010 Aug 5. PubMed PMID: 20691757. [WB, r]
- Scotti E, Hong C, Yoshinaga Y, et al. Targeted disruption of the Idol gene alters cellular regulation of the LDLR by sterols and LXR agonists. Mol Cell Biol. 2011 Feb 22. [PMID: 21343340]
more... - Wahrle SE, Jiang H, Parsadanian M, Kim J, Li A, Knoten A, Jain S, Hirsch-Reinshagen V, Wellington CL, Bales KR, Paul SM, Holtzman DM. Overexpression of ABCA1 reduces amyloid deposition in the PDAPP mouse model of Alzheimer disease. J Clin Invest. 2008 Feb;118(2):671-82.
- Wang J, Zhang Z-R, Chou C-F, et al. Cyclosporine stimulates the renal epithelial sodium channel by elevating cholesterol. Am J Physiol Renal Physiol. 2009 Feb;296(2):F284-90. [pubmed: 19091785]
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Jump to: Conjugated Antibodies, Positive Controls, Peptides and Proteins, Primary Antibodies, RNAi, Secondary Antibodies
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Related ProductsConjugated AntibodiesPositive ControlsPeptides and ProteinsPrimary Antibodies (17)| Name | Catalog# | Reactivity | Applications | Images | Publications | Reviews | |
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| ABCA1 Antibody | NB400-105 | Ha, Hu, Mu, Rt | FACS, ICC, IF, IHC-P, IP, WB | (4) | (113) | | | | ABCA1 Antibody (3A1.891.3) - Astrocyte Marker | NB400-164 | Hu(-), Mu | WB | (1) | (2) | | | | ABCA1 Antibody (5A1-1422.11) | NB400-165 | Mu | FACS | (1) | (2) | | | | ABCA1 Antibody (A00121.01) - Astrocyte Marker | NB100-1663 | Ch, Hu, Mu | IHC-P, PEP-ELISA, WB | (2) | (3) | | | | ABCA1 Antibody | NBP1-69012 | Hu, Mu | WB | (1) | | | | | ... and 12 more. See All » |
RNAi (1)Secondary Antibodies| Name | Catalog# | Reactivity | Applications | Images | Publications | Reviews | |
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| Mouse IgG Antibody [Biotin] | NB720-B | Mu | ELISA, IHC-P, WB | | | | | | Mouse IgG Antibody [HRP] | NB720-H | Mu | ELISA, ICC, IHC-P, WB | | | | | | Mouse IgG Antibody [Alkaline Phosphatase] | NB720-AP | Mu | ELISA, ICC, IHC-P, WB | | | | | | Mouse IgG Antibody [FITC] | NB720-F | Mu | ICC, IHC-P | | (2) | | | | Mouse IgG Antibody | NB120-7056 | Bv(-), Ch(-), Eq(-), Gp(-), Gt(-), Ha(-), Hu(-), Mu, Rb(-), Rt(-), Sh(-) | ELISA, IHC-P, IP, WB | | | | | | See All » |
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