ABCB5 Antibody

Species: Hu Applications: ELISA Clonality: Polyclonal	Gene: ABCB5 Purity: Affinity purified Host: Rabbit
Specificity: This product is specific for Human ABCB5.
See All ABCB5 Products See All ABCB5 Related Products: Lysates Primary Antibodies RNAi
*Note not all species have been tested for reactivity. Only those species listed have been tested. We cannot make any guarantees about additional reactivities or cross reactivities beyond those that have been tested. This antibody may or may not react with other species.

Immunogen:	This antibody is specific for the N Terminus Region of the target protein.

Entrez:	340273 (Human)
Swiss Prot:	Q2M3G0 (Human)
Related Genes:	ABCC8, ABCA1, ABCB1, APOA1, ABCB1B, RFC4, RFC1, KLRA1, UGT1A6, BRP1, RFC2, ATP6V0A1, TCF3, BCL2A1A, ABCC1, CFTR, ABCC9, ABCG2, ABCB1A, KCNJ11, PPARG, ABCC2, ABCA13, MSH3, TBC1D9, ABCE1, ABCC6, MDM4, MVP, PRL2C2, ABCC3, PRL2C3, ABCA3, PPARA, LRP6, ABCB11, ABCC10, ABCD3, ABCC4, EXOSC10

ATP-Binding Cassette proteins comprise a superfamily of transporters with a wide variety of substrates. ABCB5 is a novel member of the human P-glycoprotein family. It functions as a determinant of membrane potential and regulator of cell fusion in physiologic skin progenitor cells. Cell fusion is thought to contribute to tissue differentiation. ABCB5 is predominantly expressed in melanoma cells and is a novel molecular marker for a distinct subset of chemoresistant stem cell phenotype-expressing tumor cells among human epidermal melanocytes. It has been identified as a novel drug transporter in human malignant melanoma. ABCB5 is a rhodamine efflux transporter. This antibody product is intended to be used to confirm cellular localization and expression level of ABCB5.

Reactivity:	Human.

Uses:

The concentration for this product is lot dependent. Check product vial for current lot concentration. Typically concentration ranges from 0.5 to 1.5 mg/ml. This antibody is useful for Western Blot. This product has been QC tested by ELISA using a recombinant protein. Why use an untested antibody? SDIX’s GAT technology means these antibodies were produced through in vivo expression of the antigen, meaning the antibodies are highly specific to the expressed protein. Applications such as IHC and WB are more likely to be successful with GAT antibodies, than with any other production process.

Dilutions:

Western Blot 1:5000-1:20000,ELISA

Manufactured by SDIX's proprietary Genomic Antibody Technology™. GAT FAQs.

Buffer:	20 mM Potassium Phosphate, 150 mM Sodium Chloride, pH 7.0
Storage:	Store at -20C. Avoid freeze-thaw cycles.
Preservative:	No Preservative
Limitations:	This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months.