26S Proteasome regulatory subunit p55 Lysate (NBL1-14897)
26S Proteasome regulatory subunit p55 Lysate
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Distributor Data...
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MGC75406, Rpn5, p55 |
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26S Proteasome regulatory subunit p55 Lysate Summary: | | Gene: | PSMD12 |
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| Purity: | Protein |
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| | Specificity: | Homo sapiens proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 (PSMD12), transcript variant 1, mRNA. |
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| | Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur. |
View Additional 26S Proteasome regulatory subunit p55 Products 26S Proteasome regulatory subunit p55 Lysate Details: | Immunogen: | The lysate was created in HEK293T cells, using plasmid ID RC205680 and based on accession number NM_002816. The protein contains a C-terminal DDK tag. |
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Lysate Details: | Type: | Overexpression | Life Stage: | Adult | | Protein State: | Native | Tissue Condition: | Normal | | Sub-cellular Fraction: | Whole |
| Uses: | This product is intended for use as a positive control in Western Blot. You will receive the lysate (100ug), and an empty vector negative control (100 ug). |
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| Dilutions: | Western Blot |
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| TMW: | 52.7 kDa |
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| Unit Size: | 0.1 mg |
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| Concentration: | 1.0 mg/ml |
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Notes: This product is manufactured by and sold under license from OriGene Technologies and its use is limited solely for research purposes. Please note that “1 mg/ml” refers to the total protein concentration and that the specific protein concentration is not determined at this time. Packaging: | Storage: | Store at -80 °C. Avoid freeze-thaw cycles. |
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| Buffer: | RIPA buffer |
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| Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. |
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Background: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 3. [provided by RefSeq]. Transcript Variant: This variant (1) encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
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26S Proteasome regulatory subunit p55 Lysate Images (1) Western Blot: 26S Proteasome regulatory subunit p55 Lysate [NBL1-14897] - Western Blot experiments.
Left-Control; Right -Over-expression Lysate for PSMD12 |
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