5HT2B Receptor Antibody (19510002)
5HT2B Receptor Antibody
Summary:
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| *Note not all species have been tested for reactivity. Only those species listed have been tested. We cannot make any guarantees about additional reactivities or cross reactivities beyond those that have been tested. This antibody may or may not react with other species. | |||||||||||||
Details:
| Immunogen: | This antibody is specific for the Middle Region of the target protein. |
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Gene Symbol: HTR2B
| Swiss Prot: | NM_000867 (Human) |
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| Related Genes: | HTR2C, HTR1B, HTR1A, HTR3A, HTR7, SLC6A4, MAPK3, HTR6, MAPK1, HTR1D, HTR1F, CC2D1A, PRKCG, TNFRSF11A, GNAQ, CALR, FOS, AOX1, TAF8, CD74, ADAM17, QPCT, HTR5A, TNF, ST6GALNAC2, GCNT2, VIPR1, EPHB2, MAPK12, MAOA, ELANE, EPHB1, EDN1, DIO3, IFI205, SLC3A1, DIO2, SCTR, TMIE, NOS2 |
Background:
Multiple receptor subtypes of serotonin neurotransmitters with multiple physiologic functions have been recognized. The 5-HT-2 receptors mediate many of the central and peripheral physiologic functions of serotonin. Cardiovascular effects include contraction of blood vessels and shape changes in platelets; central nervous system effects include neuronal sensitization to tactile stimuli and mediation of hallucinogenic effects of phenylisopropylamine hallucinogens.[supplied by OMIM]
| Reactivity: | Human. |
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| Uses: | The concentration for this product is lot dependent. Check product vial for current lot concentration. Typically concentration ranges from 0.5 to 1.5 mg/ml. This antibody is useful for Western Blot. This product has been QC tested by ELISA using a recombinant protein. Why use an untested antibody? SDIX’s GAT technology means these antibodies were produced through in vivo expression of the antigen, meaning the antibodies are highly specific to the expressed protein. Applications such as IHC and WB are more likely to be successful with GAT antibodies, than with any other production process. |
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| Dilutions: | Western Blot 1:5000-1:20000,ELISA |
Notes:
Manufactured by SDIX's proprietary Genomic Antibody Technology™. GAT FAQs.
Packaging:
| Buffer: | 20 mM Potassium Phosphate, 150 mM Sodium Chloride, pH 7.0 |
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| Storage: | Store at -20C. Avoid freeze-thaw cycles. |
| Preservative: | No Preservative |
| Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. |
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Phone: 888-506-6887 |
This product is fully covered under guarantee+ |
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![Confocal immunofluorescent analysis of HeLa cells using LSD1 (C69G12) Rabbit mAb (green). Actin filaments have been labeled with Alexa Fluor 555 phalloidin (red). 5HT2B Receptor Antibody [19510002)] image](/sites/default/files/19510002=IF-IC.jpg)
![Immunohistochemistry: 5HT2B Receptor Antibody [19510002] - IHC using anti HTR2B SEQer antibody 5HT2B Receptor Antibody [19510002)] Immunohistochemistry image](/sites/default/files/19510002=IHC.jpg)
![Immunohistochemistry: 5HT2B Receptor Antibody [19510002] - B = Total human brain extract (5ug). P = Total human placenta extract (5ug). T = Total human breast tumor extract (5ug). The Genomic Antibodies stock was 1mg/ml. The blot was probed with Genomic Antibodies overnight. (1:10,000), washed, probed with goat anti rabbit-HRP conjugate at 1:5000 dilution, washed and developed with chemiluminescence (film 5-30sec exposures). 5HT2B Receptor Antibody [19510002)] Immunohistochemistry image](/sites/default/files/19510002=IHC-P_(Paraffin).jpg)
![Western Blot: 5HT2B Receptor Antibody [19510002] - Most normal and malignant cells showed a moderate or strong cytoplasmic staining. Malignant lymphomas and gliomas were either negative or weakly cytoplasmic stained. Image (malignant lymphoma) was provided courtesy of the Swedish Human Proteome Resource (HPR) Center. 5HT2B Receptor Antibody [19510002)] Western Blot image](/sites/default/files/19510002=WB.jpg)
