Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur.
View Additional 160kDa Neurofilament Medium Products
160kDa Neurofilament Medium [p Ser614, p Ser619] Antibody (EPR580(2)Y) Details:
Clone:
EPR580(2)Y
Isotype:
IgG
Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Serine 614/619 of human NF-M was used as an immunogen.
Marker:
Neuronal Marker
Modification:
p Ser614, p Ser619
Species Reactivity:
Reacts in Human.
Applications:
Uses:
This product is useful for: Western Blot, Immunoprecipitation. In Western blot this antibody detects a band at approximately 160kDa.
Dilutions:
Western Blot 1:500, Immunoprecipitation 1:30
TMW:
160 kDa
Unit Size:
0.1 ml
Concentration:
Please see the vial label for concentration.
Packaging:
Storage:
Store at -20 °C. Avoid freeze-thaw cycles.
Buffer:
50mM Tris-Glycine [pH 7.4] with 0.15M NaCl, 40% Glycerol and 0.05% BSA
Preservative:
0.01% Sodium Azide
Limitations:
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months.
Neurofilaments (NFs) are a type of intermediate filament (IF) expressed almost exclusively in neuronal cells, and in those cells most prominently in large axons, the longest cell protrusions known in vertebrates. NFs in most vertebrates are composed of three different polypeptide chains with different molecular weights (NF-H - heavy chain, NF-M - medium chain and NF-L - light chain). The three NF subunits share sequence and structural similarity in a coiled-coil core domain, but differ in the length and sequence of their N-termini and more dramatically of their C-termini which in the case of NF-M and NF-H form the flexible extensions that link NFs to each other and to other elements in the cytoplasm.