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14-3-3 zeta [p Ser58] Antibody

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Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NB100-81766
    • Availability
      Product Discontinued

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14-3-3 zeta [p Ser58] Antibody Summary

Immunogen
The antiserum was produced against synthesized phosphopeptide derived from human 14-3-3 around the phosphorylation site of serine 58 (R-S-SP-W-R) (NP_001129171.1)
Modification
p Ser58
Specificity
14-3-3 (specific to Phospho-Ser58) detects endogenous levels of 14-3-3 only when phosphorylated at serine 58.
Clonality
Polyclonal
Host
Rabbit
Gene
YWHAZ
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 1:100-1:200
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:50-1:100
  • Western Blot 1:500-1:1000
Theoretical MW
28 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Control
14-3-3 zeta Overexpression Lysate

Reactivity Notes

Human, Mouse, Rat

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, and 50% glycerol.
Preservative
0.02% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for 14-3-3 zeta [p Ser58] Antibody

  • 1433 zeta
  • 14-3-3 zeta
  • KCIP-1
  • KCIP-1MGC126532,14-3-3-zeta
  • MGC111427
  • MGC138156
  • phospho 14-3-3 zeta
  • tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, deltapolypeptide
  • tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zetapolypeptide
  • YWHAZ
  • zeta polypeptide

Background

This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. several transcript variants differing in the 5' UTR, but encoding the same protein, have been identified for this gene. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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14-3-3 zeta [p
Ser58] Antibody
NB100-81766
14-3-3 zeta [p Ser58] Antibody
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC

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Control Lysate(s)

14-3-3 zeta Overexpression Lysate

Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol YWHAZ
Entrez
Uniprot