The 14-3-3 proteins are a family of proteins involved in the regulation of apoptosis, mitogenic signaling and cell-cycle checkpoints (1). The 14-3-3 proteins are thought to be key regulators of signal transduction events mediated through their binding to serine-phosphorylated proteins (2,3). Through binding Bad, 14-3-3 prevents apoptosis by sequestering Bad to the cytosol (3).
14-3-3 alpha , 14-3-3 protein beta/alpha , brain protein 14-3-3, beta isoform , GW128 , HS1 , KCIP-1 , Protein 1054 , Protein kinase C inhibitor protein 1 , protein kinase C inhibitor protein-1 , tyrosine 3-monooxygenase/tryptophan 5-monooxygenas, tyrosine 3-monooxygenase/tryptophan 5-monooxygenas, YWHAA