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14-3-3 beta/alpha Antibody

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Product Details

Summary
Product Discontinued
View other related 14-3-3 beta/alpha Primary Antibodies

Order Details


    • Catalog Number
      NB100-65679
    • Availability
      Product Discontinued

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14-3-3 beta/alpha Antibody Summary

Immunogen
Synthetic peptide corresponding to acetylated N-terminal sequence of sheep 14-3-3 beta. Peptide sequence: Ac.TMDKSELVC
Specificity
Recognizes the acetylated N-terminal of 14-3-3 beta, and may not react with recombinant proteins that are not N-acetylated.
Clonality
Polyclonal
Host
Rabbit
Gene
YWHAB
Purity
Unpurified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin ELISAWestern Blot
  • Western Blot
Application Notes
Immunohistochemistry-Paraffin, ELISA, Western Blot In WB detects a band of approximately 30kDa in HEK293 cell lysates. This product requires antigen retrieval using heat treatment prior to staining of paraffin sections.

Reactivity Notes

Reacts with Mouse, Rabbit, Human, Rat, Bovine and Sheep.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
Whole antisera
Preservative
0.09% Sodium Azide
Purity
Unpurified

Alternate Names for 14-3-3 beta/alpha Antibody

  • 14-3-3 alpha
  • 14-3-3 beta
  • 14-3-3 protein beta/alpha
  • brain protein 14-3-3, beta isoform
  • GW128
  • HS1
  • KCIP-1
  • Protein 1054
  • Protein kinase C inhibitor protein 1
  • protein kinase C inhibitor protein-1
  • tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, alphapolypeptide
  • tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, betapolypeptide
  • YWHAA

Background

Members of the 14-3-3 family of proteins are highly conserved proteins, localized in neurons, and are axonally transported to the nerve terminals. They are also present, at lower levels, in various other eukaryotic tissues. 14-3-3 proteins appear to play important roles in a variety of signal transduction pathways, including those involved in cell cycle regulation and cell survival. Because 14-3-3 proteins bind to specific phosphoserine-containing sequences they are likely to have an important role in signaling pathways mediated by serine/threonine protein kinases. Evidence indicates 14-3-3 is required for Raf 1 kinase activity and phosphorylation among many other functions.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol YWHAB
Entrez