14-3-3 beta/alpha Antibody Summary
| Immunogen |
A synthetic peptide corresponding to N-term of human 14.3.3 beta protein. |
| Specificity |
This antibody recognizes ~28 kDa of human 14.3.3 beta. It does not react to the other isoforms. This antibody reacts with human, rat and mouse. The other species are not tested. |
| Clonality |
Polyclonal |
| Host |
Rabbit |
| Gene |
YWHAB |
| Purity |
Immunogen affinity purified |
| Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
| Dilutions |
- ELISA 0.01-0.1 ug/ml
- Immunohistochemistry
- Immunohistochemistry-Paraffin 1:100
- Immunoprecipitation 2-5 ug/ml
- Western Blot 1-2 ug/ml
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| Publications |
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Reactivity Notes
Reactive in Human, Mouse, and Rat
Packaging, Storage & Formulations
| Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
| Buffer |
Sterile TBS (pH 7.2) with antibody stabilizer |
| Preservative |
No Preservative |
| Concentration |
0.5 mg/ml |
| Purity |
Immunogen affinity purified |
Alternate Names for 14-3-3 beta/alpha Antibody
Background
The 14-3-3 proteins are a family of small, widely expressed, highly conserved cytosolic proteins. 14-3-3 proteins bind to and influence the activities of a diverse group of molecules involved in signal transduction, cell cycle regulation and apoptosis, including Raf, PKC, Bad, Cbl, and c-Bcr. Interactions between 14-3-3 and target proteins are strongly influenced by the phosphorylation state of 14-3-3 and the target protein. 14.3.3 beta is highly expressed in brain tissue. It is critical to cell transformation and mitotic signaling.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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Publications for 14-3-3 beta/alpha Antibody (NBP1-72185)(1)
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Secondary Antibodies
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